Cartilage Injuries Clinical Trials

A listing of Cartilage Injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 22 clinical trials
Assessment Micro-anatomy of the Menisci and Cartilage After Isolated Acute ACL Injury With MRI at 7T

There is an ongoing debate regarding the optimal treatment strategy in patients suffering from an acute ACL rupture. Some authors suggest that a non-operative treatment with neuromusculoskeletal rehabilitation program provides sufficient stability and effective recovery after acute injury to the ACL. Others advocate early ACL reconstruction as a first-line treatment …

osteoarthritis
imaging procedures
acl injuries
torn meniscus
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of Allogeneic UCMSCs for Treating Large Defects Knee Injury

In terms of the surgical treatment of the cartilage injury, various techniques and ways are created to repair or regenerate articular surface of synovial joint following traumatic damage or

  • 0 views
  • 29 Aug, 2021
  • 1 location
A Phase I Single Center Open Study to Assess the Safety and Efficacy of Intra-articular Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis and Chondral Defects of the Knee

Many patients with osteoarthritis of the knee fail non-operative measures and elect to have knee arthroplasty to improve their quality of life. If successful, intra-articular mesenchymal stem cell (MSC) injections into the knee may offer another viable non-operative treatment modality. Additionally, this modality may have reparative or regenerative potential, which …

chronic pain
Accepts healthy volunteers
knee pain
joint reconstruction
total knee replacement
  • 164 views
  • 20 Sep, 2022
  • 1 location
Better and Safer Return to Sport (BEAST)

A prospective cohort design will be used to assess differences in outcomes between pivoting sport athletes with anterior cruciate ligament reconstruction (ACLR) who follow usual care and those who follow a treatment algorithm with a RTS and rehabilitation tool. Athletes aged 15-40 at injury with primary ACLR who express a …

anterior cruciate ligament reconstruction
ligament reconstruction
acl injuries
  • 0 views
  • 15 Feb, 2022
  • 2 locations
How to Best Treat Anterior Cruciate Ligament Injuries

The project is a pragmatic registry-based RCT aiming to investigate ACL injury treatment. Study results will help fill knowledge gaps, facilitate shared decision making and strengthen patient treatment. Included patients will be randomized to (1) early ACL surgery followed by rehabilitation or (2) active rehabilitation with optional delayed surgery if …

acl injuries
  • 0 views
  • 22 Mar, 2022
  • 2 locations
Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection

  • 0 views
  • 23 Jul, 2021
  • 1 location
Prospective Registry of Anterior Cruciate Ligament Reconstructions

The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. This study is a registry of all patients having knee surgery at our institution performed by 4 fellowship-trained …

acl injuries
knee surgery
  • 0 views
  • 25 May, 2022
  • 1 location
Cartilage Injury and Remodeling After ACL Rupture and Reconstruction: Functional Imaging and Biomarkers

The proposed study will establish novel relationships between intra-articular MSC recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream alterations in cartilage composition and morphology to provide novel insights into the pathoetiology of PTOA after ACL injury and reconstruction.

ligament tears
autograft
imaging procedures
acl injuries
  • 0 views
  • 30 Jul, 2021
  • 1 location
Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:

The proposed study will establish novel relationships between intra-articular mesenchymal stem cell (MSC) recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream alterations in cartilage composition and morphology to provide novel insights into the pathoetiology of post-traumatic osteoarthritis (PTOA) after ACL injury and reconstruction. …

arthritis
anterior cruciate ligament reconstruction
reconstructive surgery
cruciate ligament ruptures
knee injury trauma
  • 12 views
  • 22 Mar, 2022
  • 1 location
ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry

The primary objective of this registry is to obtain long-term outcomes on ProChondrix CR in cartilage repair procedures of the knee, ankle, foot and hip.

Accepts healthy volunteers
  • 44 views
  • 25 Mar, 2022
  • 6 locations