Cutaneous Lupus Erythematosus Clinical Trials

A listing of Cutaneous Lupus Erythematosus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 16 clinical trials
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

The purpose of this study is to assess the safety, efficacy, and tolerability of deucravacitinib (BMS-986165) compared with placebo in participants with active discoid and/or subacute cutaneous

  • 10 views
  • 23 Jul, 2022
  • 27 locations
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 3 views
  • 08 Aug, 2022
  • 49 locations
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 19 views
  • 10 Aug, 2022
  • 49 locations
Study of M5049 in CLE and SLE Participants

This study is to evaluate the safety, tolerability and pharmacokinetics (PK) of orally administered M5049 in participants with systemic lupus erythematosus (SLE) or cutaneous lupus erythematosus

cutaneous lupus
lupus
  • 4 views
  • 21 Jul, 2022
  • 10 locations
The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)

(SLE) and cutaneous lupus erythematosus (CLE; subacute cutaneous lupus erythematosus [SCLE] and/or discoid lupus erythematosus [DLE]) participants in a randomized, double-blind, placebo-controlled

cutaneous lupus
estrogen
corticosteroids
lupus
  • 0 views
  • 11 Aug, 2022
  • 31 locations
A Study to Assess the Safety and Drug Levels of BMS-986256 in Participants With Active Cutaneous Lupus Erythematosus

The purpose of this study is to assess the safety and drug levels of BMS-986256 in participants with cutaneous lupus erythematosus.

systemic lupus erythematosus
drug levels
skin lesion
  • 1 views
  • 10 Jul, 2022
  • 1 location
Low-dose UVA1 Radiation in Cutaneous Lupus Patients

The investigators are conducting an open-label clinical trial determining the effects of UVA1 phototherapy on cutaneous lupus (CLE) patients. Past research on systemic lupus (SLE) subjects indicates that this treatment is likely to be effective in treating cutaneous lupus with few side effects. The fact that most CLE patients are …

phototherapy
  • 48 views
  • 10 Mar, 2022
  • 1 location
Efficacy and Safety of Topical Nicotinamide in Treatment of Discoid Lupus Erythematosus

Cutaneous lupus erythematosus (CLE) is lupus affecting the skin. In this autoimmune disease, the body's immune system attacks healthy skin. There are 3 main types: Acute cutaneous lupus

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus

This 76-week, 3-part Phase 1b/2 study is intended to evaluate the pharmacological properties (pharmacokinetics and pharmacodynamics), safety, tolerability and preliminary effectiveness of TOFA administrated to young adults (18-45 years) with moderately to severely active SLE-CL. Subjects will be studied at the Cincinnati Children's Hospital Medical Center (CCHMC) and in Cleveland …

leflunomide
prednisone
tofacitinib
lupus
  • 72 views
  • 24 Jul, 2022
  • 2 locations
Cutaneous Lupus Registry

lupus erythematosus represents the skin manifestations of systemic lupus erythematosus, and can appear in people with or without systemic lupus. It is a mentally, physically, and emotionally

Accepts healthy volunteers
  • 30 views
  • 12 Nov, 2021
  • 1 location