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Organ Transplant - Pediatric Clinical Trials

A listing of Organ Transplant - Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (39) clinical trials

OCS Lung TOP Registry

This is an all-comers registry that will enroll: Consented patients who receive OCS preserved double lung transplants from either standard criteria donors or donors initially deemed unacceptable; and Consented patients who receive a single lung transplant from OCS preserved lung pairs from either standard criteria donors or donors initially deemed …

Phase N/A

Testing the Effect of KnowMAP (Knowledge Management for Renal Transplant Recipients). A Randomized Controlled Study

Every year about 250-300 kidney transplantations are performed at Oslo University Hospital in Norway. Considerable improvements have recently emerged within kidney transplantation in relation to survival and quality of life. However, after transplantation, adherence to immunosuppressive drug therapy and other medical advices is crucial for staying healthy, keeping the graft, …

Phase N/A

HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients

This study will evaluate if receiving a liver transplant from an HIV-infected deceased liver donor is safe with regards to survival and major transplant-related and HIV-related complications compared to receiving a liver from an HIV-uninfected deceased liver donor (HIVD-). Those participants who have accepted an HIVD- organ will be randomized …

Phase N/A

HOPE in Action Prospective Multicenter Clinical Trial of Deceased HIVD+ Kidney Transplants for HIV+ Recipients

This study will evaluate if receiving a kidney transplant from an HIV-infected deceased kidney donor is safe with regards to survival and major transplant-related and HIV-related complications compared to receiving a kidney from an HIV-uninfected deceased kidney donor (HIVD-). Those participants who have accepted an HIVD- organ will be randomized …

Phase N/A

MRI Technical Development and Applications in Kidney Disease

Specific Aims The overall objective is to develop and validate MRI methods for the evaluation and monitoring of renal status and associated cerebrovascular effects of renal dysfunction and treatment. The proposed project include two phases: 1) MRI technical development and validation with reproducibility studies; 2) clinical pilot studies with two …

Phase N/A

Assessment of the Impact of COVID-19 on Transplant Patients and on Patients Awaiting Transplantation

Transplant Centres (TCs) serve a unique patient population, those with end-organ disease who are either waiting for, or who have received, a solid-organ transplant. For transplant candidates, TCs help weigh the threat of their current condition against the intended benefits and associated risks of transplantation, which include major-surgery and chronic …

Phase N/A

Biomarkers Predicting Successful Tacrolimus Withdrawal and Everolimus (Zortress) Monotherapy Early After Liver Transplantation

Most patients who get a liver transplant must take immunosuppressants for the rest of their lives. However, this has occurred at the expense of chronic CNI toxicity, e.g. chronic kidney disease (CKD), metabolic complications, infections and malignancy. Everolimus (EVL) is a drug that may stabilize or improve kidney function for …

Phase N/A

Precision Risk Stratification in Kidney Transplant Patients - EU-TRAIN

Allograft rejection is still a major threat to allografts with thousands of allografts failing every year worldwide due to organ rejection, with immediate consequences for the patients in terms of mortality and morbidity. With a prevalence around 20% in the first-year post transplant, rejection also carries high economic impact representing …

Phase N/A

The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation

Study purposes: To evaluate the safety and efficacy of micro-energy ultrasound in the treatment of renal dysfunction after renal transplantation by measuring serum creatinine, urine volume, urea nitrogen, and transplanted kidney ultrasound, etc. Study design: This is a randomized, double-blind, controlled, multicenter clinical trial. Study objects: Patients with mild to …

Phase N/A

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

Cardiovascular disease is the commonest cause of death while on the kidney transplant waiting list and after transplantation. Current standard care involves screening for coronary artery disease prior to waitlist entry, then every 1-2 years, according to perceived risk, until transplanted. The aim of screening is two-fold. Firstly to identify …

Phase N/A