Organ Transplant - Pediatric Clinical Trials

A listing of Organ Transplant - Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 85 clinical trials
Contrast-Enhanced Ultrasound for Kidney Transplant

Contrast-enhanced ultrasound (CEUS) is a promising non-invasive imaging tool that may aid in the early detection of kidney transplant complications, such as delayed graft function (DGF) and acute allograft rejection. The technique uses an intravenous contrast agent to improve organ visualization with standard duplex ultrasound equipment. A number of FDA-approved …

delayed graft function
kidney transplant
contrast-enhanced ultrasound
  • 32 views
  • 26 Jan, 2021
  • 1 location
Evaluation of 2 Techniques of Apheresis to Desensitize ABO Incompatible Kidney Transplant Candidates

Kidney transplantation is the treatment of choice for end-stage renal disease. ABO incompatible (ABOi) living donor kidney transplantation is one of the best ways to expand the donors' pool. However, breaking the ABO barrier is possible only with a preconditioning regimen that includes 1) an immunosuppressive strategy using a B-cell …

immunosuppressants
nephropathy
kidney transplant
calcineurin inhibitor
immunosuppressive agents
  • 10 views
  • 25 Jan, 2021
  • 1 location
3-month Screening Biopsy to Optimize the Immunosuppression in Renal Transplantation

Renal transplantation represents currently the best therapeutic alternative for end-stage renal failure, not only in terms of patient outcomes (better quality of life and longer survival), but also in terms of costs for the society. Progress achieved in the last 20 years has resulted in a drastic reduction of the …

diabetes
cancer
immunosuppressants
kidney biopsy
corticosteroids
  • 21 views
  • 11 Jun, 2021
  • 22 locations
Magnesium Replacement and Hyperglycemia After Kidney Transplantation

The insulin receptor is dependent on magnesium and hypomagnesemia is associated with increased insulin resistance and decreased insulin secretion and action. Recent data suggest that hypomagnesemia may play a role in development of type 2 diabetes. Kidney transplantation patients have low plasma magnesium levels, partly due to treatment with calcineurin …

diabetes
kidney transplant
calcineurin inhibitor
  • 0 views
  • 25 Jan, 2021
  • 1 location
Qualitative and Quantitative Evaluation of Vascular Flows of Radial Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI

Allotransplants of vascularized composite tissues are subject to chronic vascular rejection, which can lead to graft loss. Currently, no imaging technique allows a reproducible quantitative exploration of the arterial trees of the hand, and therefore a satisfactory monitoring of transplants. Since 2014, flow MRI has been applied to the analysis …

doppler ultrasound
  • 0 views
  • 27 Jan, 2021
  • 1 location
Cell Therapy for Immunomodulation in Kidney Transplantation

This study investigates treatment with recipient regulatory T cells and donor bone marrow together with tocilizumab for immunomodulation in living donor kidney transplant recipients.

immunosuppressive agents
kidney transplant
immunosuppressants
blood type
  • 0 views
  • 26 Jan, 2021
  • 1 location
Belatacept in De Novo Heart Transplantation

The purpose of this study is to determine if Belatacept is safe to give to adult heart transplant recipients. Belatacept (NULOJIX) is an anti-rejection medication that is available through a prescription from a doctor. In this research study, belatacept is being used in an investigational manner (not for the purpose …

influenza
heart transplant
drug trials
hepatitis b
nulojix
  • 20 views
  • 26 Jan, 2021
Functional Non Specific Immunity Monitoring After Kidney Transplantation Using an Interferon Gamma Test

The best renal replacement therapy is kidney transplantation. It improves end-stage renal kidney disease (ESRD) patients quality of life and increases their survival, but still remains risky. Morbidity in kidney transplantation is dominated by two main complications : acute graft rejection and infections. To maintain an accurate balance between rejection …

  • 0 views
  • 22 Jan, 2021
Outcomes of Transrenal Artery Perfusion Versus Transrenal Vein Perfusion Using LifePort for Deceased Donor Kidney Transplantation

The main objective of this study is to compare the outcomes of transrenal artery perfusion versus transrenal vein perfusion using LifePort for deceased donor kidney transplantation. Patients registered in the National Dialysis and Transplant Registry awaiting deceased donor kidney transplantation were included. Delayed graft function (DGF) or primary nonfunction (PNF) …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Impact of Infectious Diseases Consultation on Vaccination Coverage Among People Waiting for a Kidney Transplant at the Clermont-Ferrand Hospital

Solid-organ transplant patients are at increased risk of infectious diseases. Among this population, infectious diseases may be life-threatening or lead to graft rejection. Their prevention is an important challenge. Despite specific national recommendations, vaccination is underutilized. That is why we propose a dedicated infectious diseases consultation during pre-kidney transplantation assessment.

  • 0 views
  • 21 Mar, 2021
  • 1 location