Organ Transplant - Pediatric Clinical Trials

A listing of Organ Transplant - Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 85 clinical trials
Evaluate the Efficacy and Safety of 'Immuncell-LC' in Patients Undergoing Liver Transplantation

The purpose of this study is to investigate and validate the maximum tolerated dose (MTD) or maximum available dose (MFD), safety and efficacy on patients with hepatocellular carcinoma beyond Milan criteria who undergo liver transplantation.

absolute neutrophil count
platelet count
hepatocellular carcinoma
  • 12 views
  • 26 Apr, 2021
  • 1 location
Lung Transplant G0 (LTGO): Improving Self-Management of Exercise After Lung Transplantation

Estimated costs, from thirty days prior to lung transplant up through six months post surgery, exceed 1 million dollars per patient and routine medical costs average approximately fifty thousand dollars per year thereafter. Prior to transplant, lung transplant recipients self restrict activity due to severe respiratory limitations, resulting in reduced …

immunosuppression
hypertension
lung function
  • 2 views
  • 17 Feb, 2021
  • 1 location
Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation

The aim of this study is to investigate whether therapy with intravenous iron carboxymaltose in patients with iron deficiency anemia (IDA) listed for orthotopic liver transplantation (OLT) increases hemoglobin concentrations and reduces intraoperative transfusion of packed red blood cells (PRBCs). The investigators hypothesize that therapy with intravenous iron will increase …

orthotopic liver transplant
blood transfusion
packed red blood cells
  • 0 views
  • 25 Jan, 2021
  • 1 location
mDOT for Immunosuppressant Adherence in Adolescent Liver Transplant Recipients

The investigators are interested in whether or not the use of a mobile health (mHealth) application increases the rate of immunosuppression medication adherence among adolescent liver transplant recipients. The investigators aim to test this by recruiting adolescent (ages 14-21) liver transplant recipients to use an mHealth application to record themselves …

immunosuppressants
immunosuppression
liver transplant
immunosuppressive agents
  • 0 views
  • 25 Jan, 2021
  • 1 location
Mediterranean Diet Post-liver Transplantation

The purpose of this study is to study the effects of a structured Mediterranean dietary program on prevention of weight gain, promotion of heart health and prevention of fatty liver disease after liver transplantation.

  • 0 views
  • 16 Apr, 2021
  • 1 location
New Prognostic Predictive Models of Mortality of Decompensated Cirrhotic Patients Waiting for Liver Transplantation

The MELD score is a predictive model of cirrhosis mortality used in France since 2007 to prioritize access to liver transplantation for patients enrolled in the national waiting list. The predictive value of this score was recently revised downward with a C index of the order of 0.65-0.67 and 20% …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Planned Semi-Elective Lung Tx Study

In the current practice of lung transplantation, transplants are performed on a 24/7 schedule with a significant amount of procedures occurring overnight in order to minimize organ ischemic time. However, transplantation during the day time may lead to several advantages related to patient safety, including the presence of rested staff …

  • 0 views
  • 26 Jan, 2021
  • 1 location
The Long-term Effect of Marine Omega-3 Fatty Acid Supplementation in Renal Transplantation

This is a long-term intervention study on the effects of marine n-3 PUFAs in renal transplantation. Our hypothesis is that patients treated with marine n-3 PUFA supplementation will have less decline in kidney transplant function compared to patients treated with placebo.

kidney transplant
  • 158 views
  • 26 Jan, 2021
  • 6 locations
Systematic Transplantectomy Versus Conventional Care After Kidney Graft Failure

Our hypothesis is early and systematic transplantectomy under a well-conducted immunosuppression is associated with a decreased risk of anti-HLA immunization against a conservative attitude including a gradual reduction of immunosuppression, with or without a transplantectomy performed for cause (clinical event). Observation or Investigation Method Used : The study is : …

withdrawn
immunosuppressants
corticosteroids
dialysis
immunosuppressive agents
  • 19 views
  • 14 Jun, 2021
  • 39 locations
Tolerance by Engaging Antigen During Cellular Homeostasis

Anti-rejection medicines, also known as immunosuppressive drugs, are prescribed to organ transplant recipients to prevent rejection of the new organ. Long-term use of these medicines places transplant recipients at higher risk of serious infections and certain types of cancer. The purpose of this study is to determine if: it is …

immunosuppressants
cancer
immunosuppressive agents
immunosuppression
sirolimus
  • 25 views
  • 14 May, 2021
  • 1 location