Organ Transplant - Pediatric Clinical Trials

A listing of Organ Transplant - Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 74 clinical trials
Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management

Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs. Despite undeniable success in the short term, due to major advances in surgery, medicine and research, transplant recipients continue to face the …

heart transplant
  • 21 Oct, 2021
  • 3 locations
Cyclosporine A Pretreatment and Kidney Graft Function (Cys-A-Rein)

Organ donors included in the study are randomized to a control group or an intervention group receiving 2.5 mg/kg of cyclosporine A before organ procurement. Harvested kidneys from these patients are transplanted to chronic kidney insufficiency patients. According to the pretreatment of the transplant, delayed graft function during the first …

delayed graft function
chronic renal insufficiency
  • 27 Feb, 2022
  • 1 location
Impact of the Use of Remote Monitoring in the Follow-up of the Renal Transplant Patient. (APT'x)

Transplant Centers are facing new organisational challenges with regards to the growing number of patients they have to follow-up. We have developed and assessed the feasibility of using a novel web application permitting a medically-tailored follow-up of stable renal transplanted outpatients: Ap'TELECARE. This novel approach is likely to facilitate the …

  • 09 Feb, 2022
  • 3 locations
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) …

heart transplant
organ transplantation
heart disease
  • 09 Mar, 2021
  • 9 locations
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (CARSK)

The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major …

coronary disease
kidney failure
renal failure
  • 02 Mar, 2022
  • 15 locations
Safety and Feasibility of Normothermic Machine Perfusion to Preserve and Evaluate Orphan Livers

Orphan livers are organs that have been declined for clinical use by all centers due to their marginality. The current standard of care of liver preservation before transplant is cold storage. NMP may allow these livers to be evaluated before transplantation. NMP has already been used in a clinical setting …

hepatocellular carcinoma
perfusion of liver
  • 27 Feb, 2022
  • 1 location
A Study of Patient Adherence and Convenience to Immunosuppressive Agents in Newly Liver Transplant

A study of patient adherence and convenience to immunosuppressive agents in newly liver transplant recipients - a prospective, multi-center, open-labeled, randomized clinical trial for comparison between once-daily early conversion and twice-daily tacrolimus formulation.

immunosuppressive agents
  • 05 Mar, 2022
  • 1 location
Evaluate the Efficacy and Safety of 'Immuncell-LC' in Patients Undergoing Liver Transplantation

The purpose of this study is to investigate and validate the maximum tolerated dose (MTD) or maximum available dose (MFD), safety and efficacy on patients with hepatocellular carcinoma beyond Milan criteria who undergo liver transplantation.

hepatocellular carcinoma
absolute neutrophil count
platelet count
  • 09 Feb, 2022
  • 1 location
Hypothermic Oxygenated Perfusion for Extended Criteria Donors in Liver Transplantation (HOPExt) (HOPExt)

Given the scarce donor supply, an increasing number of so-called marginal or extended criteria donor (ECD) organs have been used for liver transplantation. These ECD liver grafts are, however, known to be associated with a higher rate of early allograft dysfunction (EAD) and primary non-function because of a greater vulnerability …

reperfusion injury
  • 24 Mar, 2022
  • 6 locations
Activity Coaching in Patients Post Lung Transplantation

Lung transplantation is an ultimate, effective treatment option for selected patients with end stage lung disease, improving quality of life and extending survival. Because of the improved survival during the last decades, enhancing the long term condition after lung transplantation has now become a focus for disease management. The co-presence …

pulmonary disease
lung function
  • 25 Feb, 2022
  • 1 location