Organ Transplant - Pediatric Clinical Trials

A listing of Organ Transplant - Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 82 clinical trials
Impact of the Use of Remote Monitoring in the Follow-up of the Renal Transplant Patient.

Transplant Centers are facing new organisational challenges with regards to the growing number of patients they have to follow-up. We have developed and assessed the feasibility of using a novel web application permitting a medically-tailored follow-up of stable renal transplanted outpatients: Ap'TELECARE. This novel approach is likely to facilitate the …

metastases
  • 6 views
  • 16 Apr, 2021
  • 3 locations
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) …

lupus
coagulopathy
heart disease
organ transplantation
heart transplantation
  • 0 views
  • 09 Mar, 2021
  • 9 locations
Cyclosporine A Pretreatment and Kidney Graft Function

Organ donors included in the study are randomized to a control group or an intervention group receiving 2.5 mg/kg of cyclosporine A before organ procurement. Harvested kidneys from these patients are transplanted to chronic kidney insufficiency patients. According to the pretreatment of the transplant, delayed graft function during the first …

chronic renal insufficiency
delayed graft function
cyclosporine
  • 18 views
  • 24 Jan, 2021
  • 1 location
A Study of CMV Vaccine (HB-101) in Kidney Transplant Patients

HB-101 is a bivalent recombinant vaccine against human CMV infection. This is a randomized, placebo-controlled, phase 2 study to assess the safety, reactogenicity, immunogenicity, and efficacy of HB-101 in CMV-Seronegative patients receiving a kidney transplant from a CMV-Seropositive living donor and CMV-Seropositive patients.Patients enrolled should have a living donor kidney …

kidney transplant
  • 42 views
  • 08 May, 2021
  • 44 locations
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major …

kidney transplant
renal failure
arteriopathy
metastases
kidney failure
  • 1 views
  • 06 May, 2021
  • 19 locations
Evaluate the Efficacy and Safety of 'Immuncell-LC' in Patients Undergoing Liver Transplantation

The purpose of this study is to investigate and validate the maximum tolerated dose (MTD) or maximum available dose (MFD), safety and efficacy on patients with hepatocellular carcinoma beyond Milan criteria who undergo liver transplantation.

absolute neutrophil count
platelet count
hepatocellular carcinoma
  • 12 views
  • 26 Apr, 2021
  • 1 location
Study to Evaluate Performance of the Organ Recovery Systems LifePort Liver Transporter System a Machine Perfusion System for Liver Transplant

Comparison of hypothermic machine perfusion of livers to standard of care (static cold storage).

cold
liver transplant
  • 7 views
  • 18 Jun, 2021
  • 8 locations
Lung Transplant G0 (LTGO): Improving Self-Management of Exercise After Lung Transplantation

Estimated costs, from thirty days prior to lung transplant up through six months post surgery, exceed 1 million dollars per patient and routine medical costs average approximately fifty thousand dollars per year thereafter. Prior to transplant, lung transplant recipients self restrict activity due to severe respiratory limitations, resulting in reduced …

lung function
immunosuppression
hypertension
  • 2 views
  • 17 Feb, 2021
  • 1 location
Hypothermic Oxygenated Perfusion for Extended Criteria Donors in Liver Transplantation (HOPExt)

Given the scarce donor supply, an increasing number of so-called marginal or extended criteria donor (ECD) organs have been used for liver transplantation. These ECD liver grafts are, however, known to be associated with a higher rate of early allograft dysfunction (EAD) and primary non-function because of a greater vulnerability …

steatosis
cold
reperfusion injury
  • 17 views
  • 14 Mar, 2021
  • 11 locations
mDOT for Immunosuppressant Adherence in Adolescent Liver Transplant Recipients

The investigators are interested in whether or not the use of a mobile health (mHealth) application increases the rate of immunosuppression medication adherence among adolescent liver transplant recipients. The investigators aim to test this by recruiting adolescent (ages 14-21) liver transplant recipients to use an mHealth application to record themselves …

immunosuppressants
immunosuppressive agents
liver transplant
immunosuppression
  • 0 views
  • 25 Jan, 2021
  • 1 location