Rotavirus Clinical Trials

A listing of Rotavirus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 12 clinical trials
Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

The study will evaluate safety and immunogenicity of LORV (Rotarix and RV3-BB) when TV P2-VP8, a parentally administered rotavirus vaccine is administered either concomitantly or as a prime

Accepts healthy volunteers
  • 10 views
  • 12 Nov, 2021
  • 2 locations
Efficacy Safety and Immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in Neonates

This phase III trial aims to assess the efficacy, safety and immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in neonates, lot-to-lot consistency, and antigen interference with co

  • 0 views
  • 19 Jan, 2022
  • 8 locations
A Trial to Assess the Safety Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India

The trial will be a multinational, randomized, double-blind, double-dummy, endpoint driven, group-sequential, active comparator-controlled study, in which participating infants will be randomized 1:1 to receive either: 1) 90 g of the TV P2-VP8 vaccine IM plus oral placebo, or 2) Rotarix per os (PO) plus IM placebo. Participants will receive …

  • 0 views
  • 15 Apr, 2021
  • 1 location
Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa

Despite the widespread introduction of vaccines against Rotavirus, Rotavirus continues to be a cause of significant morbidity and mortality in the developing world. This study will assess

  • 0 views
  • 28 Apr, 2021
  • 1 location
Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam

The primary objective is to measure the effect of host human genetics on the resulting immunological responses and long-term protection following rotavirus immunization of a study population of

rotarix
rotavirus
rotavirus vaccine
vaccination
  • 24 views
  • 21 Jul, 2021
  • 4 locations
COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients

), influenza H1N1, and rotavirus with good efficacy. This study will evaluate the efficacy of PVP-I as prophylaxis in Coronavirus Disease 2019 (COVID19)-negative front-line health care workers, hospital

nasopharyngeal swab
middle east respiratory syndrome
SARS
coronavirus infection
covid-19
  • 37 views
  • 16 Jun, 2021
  • 1 location
Catalysing the Containment of COVID-19

production, and interferes with SARS-CoV-2 glycosylation. It has been shown to have anti-viral activity against several viruses including Ebola, influenza, hepatitis B and C, rotavirus and norovirus.

oseltamivir
hypercytokinemia
interferon
SARS
antihypertensive drugs
  • 42 views
  • 14 Jun, 2021
  • 4 locations
Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol)

The CDC and WHO have deemed the COVID-19 virus a global pandemic of unprecedented severity in modern times. In 2019, this novel Coronavirus (COVID-19) emerged from the Asian continent and has now caused upwards of 1million deaths and over 6 million infections globally. Currently, the estimated global economic impact is …

  • 282 views
  • 31 Mar, 2021
  • 1 location
Prevention of Irinotecan Induced Diarrhea by Probiotics

Diarrhea is a relatively common complication in patients with cancer. At its inception, several mechanisms participated; malabsorption on the basis of mucositis induced by chemotherapy, dysbiosis induced by broad-spectrum antibiotics and predisposition to infectious diarrhea in immunocompromised patients. Some cytostatics and their metabolites can also induce diarrhea directly due to …

antibiotic therapy
antibiotics
strain
cancer
dysentery
  • 0 views
  • 30 Apr, 2021
  • 1 location
Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial

Severe Alcoholic hepatitis, defined by modified Maddrey's Discriminant Function (DF) ≥32, is associated with significant morbidity and mortality.(1,2) Of the various treatment modalities evaluated for treatment of Severe Alcoholic hepatitis, corticosteroids have been the most extensively studied.(1) Five out of 13 randomized controlled trials, and four out of 5 meta-analysis …

encephalopathy
jaundice
glucocorticoids
milk powder
corticosteroids
  • 5 views
  • 21 Dec, 2021
  • 1 location