Chronic Lymphocytic Leukemia Clinical Trials

A listing of Chronic Lymphocytic Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 299 clinical trials
Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

, and venetoclax, given in combination as a treatment for CLL and/or SLL.

mantle cell lymphoma
residual tumor
chronic lymphocytic leukemia
cancer
flow cytometry
  • 22 views
  • 07 Oct, 2022
  • 7 locations
Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL

This research study is studying a combination of drugs as a possible treatment for chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The names of the study drugs

thrombocytopenia
obinutuzumab
lymphoma
venetoclax
neutrophil count
  • 0 views
  • 22 Aug, 2021
  • 3 locations
Personalized Multi-peptide Vaccination in CLL Patients

The aim of this study is to evaluate the efficiency along with safety and toxicity of a personalizied multi-peptide vaccine in combination with the TLR1/2 ligand XS15 in CLL patients undergoing

remission
constitutional symptoms
lymphadenopathy
flow cytometry
ibrutinib
  • 0 views
  • 18 Sep, 2021
  • 1 location
Belimumab in Patients With Chronic Lymphocytic Leukemia (BeliVeR)

This study is a phase II trial of belimumab in combination with rituximab/venetoclax in patients with refractory or relapsed chronic lymphocytic leukemia (CLL). Treatment of CLL has drastically

  • 0 views
  • 25 Mar, 2022
Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

This study will combine both T cells and antibodies in order to create a more effective treatment. The treatment tested in this study uses modified T-cells called Autologous T Lymphocyte Chimeric Antigen Receptor (ATLCAR) cells targeted against the kappa light chain antibody on cancer cells. For this study, the anti-kappa …

lymphoma cells
mantle cell lymphoma
cancer
monoclonal antibodies
refractory follicular lymphoma
  • 15 views
  • 09 Dec, 2021
  • 1 location
Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL (AVO)

This research study is evaluating the combination of three drugs - acalabrutinib, venetoclax, and obinutuzumab -- as a possible treatment for chronic lymphocytic leukemia (CLL). The drugs

cancer
venetoclax
monoclonal antibodies
fever
measurable disease
  • 233 views
  • 19 Jun, 2022
  • 3 locations
Copanlisib Plus Ibrutinib or Acalabrutinib in R/R CLL

six months for relapsed/refractory chronic lymphocytic leukemia (CLL). The names of the study drugs involved in this study are: Copanlisib Ibrutinib

lymphadenopathy
chronic lymphocytic leukemia
ibrutinib
neutrophil count
acalabrutinib
  • 0 views
  • 02 Jun, 2022
  • 1 location
Study to Evaluate the Safety and Preliminary Efficacy of Ibrutinib and Pembrolizumab in Patients With Chronic Lymphocytic Leukemia (CLL) or Mantle Cell Lymphoma (MCL)

been approved in the United States, Israel, and the European Union for use in adult patients with mantle cell lymphoma (MCL) and adult patients with chronic lymphocytic leukemia (CLL) who have received

tyrosine
mantle cell lymphoma
chronic lymphocytic leukemia
cancer
ibrutinib
  • 88 views
  • 04 Oct, 2022
  • 1 location
Umbralisib Plus Ublituximab (U2) in Progressive CLL After Novel Therapy

This study evaluates the efficacy and safety of umbralisib and ublituximab (U2) as salvage therapy in patients with chronic lymphocytic leukemia (CLL) who have progressed either on a BTK

chronic lymphocytic leukemia
btk inhibitor
neutrophil count
monoclonal antibodies
corticosteroids
  • 0 views
  • 26 Apr, 2022
  • 1 location
Selenious Yeast in CLL Patients w/o Indication of Chemotherapy

The purpose of this study is to evaluate the safety and effectiveness of Selenious Yeast Tablets in Chronic Lymphocytic Leukemia Patients without Indication of Chemotherapy

  • 0 views
  • 06 Dec, 2021
  • 1 location