Chronic Lymphocytic Leukemia Clinical Trials

A listing of Chronic Lymphocytic Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 316 clinical trials
A Phase 2 Study to Evaluate the Efficacy and Safety of MK-1026 in Participants With Hematologic Malignancies

The purpose of this study is to evaluate the safety and efficacy of nemtabrutinib (formerly ARQ 531) in participants with hematologic malignancies of chronic lymphocytic leukemia (CLL)/ small

leukemia
hepatitis b surface antigen
chronic lymphocytic leukemia
lymphoma
kinase inhibitor
  • 33 views
  • 22 Sep, 2022
  • 37 locations
GEN3013 Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

The trial is a global, multi-center safety trial of epcoritamab, an antibody also known as GEN3013 (DuoBody®-CD3xCD20). The trial consists of two parts: a dose-escalation part (Phase 1, first-in-human (FIH)) and an expansion part (Phase 2a). All trial participants will get epcoritamab.

monoclonal protein
chronic lymphocytic leukemia
high grade b-cell lymphoma
pet/ct scan
marginal zone lymphoma
  • 324 views
  • 13 Jul, 2022
  • 91 locations
First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas

The drug that will be investigated in the study is an antibody, GEN3009. Since this is the first study of GEN3009 in humans, the main purpose is to evaluate safety. Besides safety, the study will determine the recommended GEN3009 dose to be tested in a larger group of patients and …

leukemia
chronic lymphocytic leukemia
btk inhibitor
refractory b-cell non-hodgkin lymphoma
lymphocytic leukemia
  • 17 views
  • 28 Jul, 2022
  • 14 locations
Safety & Efficacy Study of Epcoritamab in Subjects With R/R Chronic Lymphocytic Leukemia and Richter's Syndrome (EPCORE CLL-1)

The trial is an open-label, multi-center safety and efficacy trial of epcoritamab in relapsed/refractory chronic lymphocytic leukemia (R/R CLL) and Ritcher's Syndrome (RS). The trial consists of

  • 0 views
  • 30 Jun, 2022
  • 22 locations
  • 17 views
  • 04 May, 2022
  • 8 locations
A Phase I, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Patients With Relapsed or Refractory Lymphoma

This is a Phase I, open-label, multicenter study of HMPL-523 administered orally to patients with relapsed or refractory lymphoma who have exhausted approved therapy options. This study consists of a dose escalation stage (Stage1) and a dose expansion stage (Stage 2).

leukemia
follicular lymphoma
chronic lymphocytic leukemia
marginal zone lymphoma
waldenstrom's macroglobulinemia
  • 0 views
  • 19 Sep, 2022
  • 21 locations
In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

quantitatively characterize metabolic signatures and fuel preferences of leukemic lymphocytes in patients with chronic lymphocytic leukemia (CLL). Isotopic metabolic tracers are nutrients that are chemically

cancer
chronic lymphocytic leukemia
cytopenia
lymphocytosis
Accepts healthy volunteers
  • 0 views
  • 03 Jul, 2022
  • 1 location
Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

This phase II trial studies how well zanubrutinib and rituximab work in treating patients with chronic lymphocytic leukemia or small lymphocytic lymphoma for which the patient has not received

monoclonal protein
chronic lymphocytic leukemia
lymphoma
btk inhibitor
gilbert's syndrome
  • 0 views
  • 27 Jul, 2022
  • 1 location
Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

This phase II trial tests whether acalabrutinib, venetoclax, and durvalumab work in treating patients with Richter transformation from chronic lymphocytic leukemia or small lymphocytic lymphoma

venetoclax
monoclonal protein
lymphadenopathy
lymphoma
chronic lymphocytic leukemia
  • 0 views
  • 02 Jul, 2022
  • 1 location
Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)

Background The drug venetoclax treats chronic lymphocytic leukemia (CLL). Researchers want to find better treatments for CLL. To do that, they need to learn how

venetoclax
fever
chronic lymphocytic leukemia
anemia
night sweats
  • 0 views
  • 14 Sep, 2022
  • 1 location