Desmoid Tumors Clinical Trials

A listing of Desmoid Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 12 clinical trials
A Study of AL102 in Patients With Progressing Desmoid Tumors (RINGSIDE)

The current study is designed to evaluate the efficacy and safety of AL102 in patients with progressive desmoid tumors.

MRI
measurable disease
line of therapy
  • 11 views
  • 01 Jul, 2022
  • 27 locations
A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014) in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors

This phase II trial studies the side effects and how well nirogacestat works in treating patients patients less than 18 years of age with desmoid tumors that has grown after at least one form of

cardiac dysrhythmias
tumor cells
myocardial infarction
stroke
tyrosine
  • 4 views
  • 13 Oct, 2022
  • 51 locations
DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

>Desmoid tumors Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) Malignant giant cell tumors Chordoma (closed to accrual 11/29/2018)

desmoid tumors
trophoblastic disease
remission
total bilirubin
trophoblastic tumor
  • 6651 views
  • 22 Oct, 2022
  • 752 locations
Cryotherapy in the Treatment of Desmoid Tumors

Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative

medical therapy
hormone therapy
nonsteroidal anti-inflammatory drugs
measurable disease
tamoxifen
  • 0 views
  • 22 Apr, 2022
  • 1 location
A Randomized, Double-blind, Phase Ⅲ Study of Liposomal Doxorubicin in Desmoid Tumor

The aim of this study was to evaluate the efficacy and safety of liposomal doxorubicin in the treatment of desmoid tumors. Unless the subject withdraws from the trial voluntarily, or the

metastatic disease
platelet count
nitrosoureas
renal function
tyrosine
  • 0 views
  • 21 Oct, 2022
  • 1 location
A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or does not respond to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help stop the growth of …

cancer of the ovary
tumor cells
graft versus host disease
growth factors
nitrosoureas
  • 0 views
  • 10 Oct, 2022
  • 11 locations
The TNT Protocol: A Phase 2 Study Using Talimogene Laherparepvec,Nivolumab and Trabectedin as First, Second/Third Line Therapy for Advanced Sarcoma, Including Desmoid Tumor and Chordoma (TNT)

This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.

kidney function tests
platelet count
metastatic sarcoma
advanced sarcoma
trabectedin
  • 37 views
  • 22 Oct, 2022
  • 1 location
Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors

therapy on the 3 years rate of local tumor recurrence in patients with desmoid tumors. To evaluate the Safety of 5-ALA administration. 5 years local recurrence rate.

  • 39 views
  • 08 Nov, 2020
  • 1 location
HIFU Ablation of Soft Tissue Sarcoma (SarcAblate)

> This study will recruit patients with both resectable and unresectable STS, in addition to unresectable small symptomatic desmoid tumours. 12-16 patients, and a minimum of 10 patients with

cancer chemotherapy
soft tissue sarcoma
cancer
  • 5 views
  • 21 Mar, 2022
  • 1 location
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

metastatic disease
desmoid tumors
cancer
langerhans cell histiocytosis
carcinoma
  • 366 views
  • 13 Oct, 2022
  • 128 locations