Rhabdomyosarcoma Clinical Trials

A listing of Rhabdomyosarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 29 clinical trials
Investigating Safety Tolerability Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours

  • 16 views
  • 01 Aug, 2021
  • 20 locations
Evolutionary Therapy for Rhabdomyosarcoma

This clinical trial will evaluate 4 different strategies of chemotherapy schedules in newly diagnosed participants with metastatic Fusion Positive (alveolar) Rhabdomyosarcoma. The participant

metastasis
vincristine
vinorelbine
cancer chemotherapy
actinomycin
  • 0 views
  • 21 Jul, 2021
  • 8 locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

vinorelbine) works compared to combination chemotherapy plus temsirolimus in treating patients with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle), and has an intermediate chance of

glomerular filtration rate
platelet count
vincristine
cancer chemotherapy
actinomycin
  • 292 views
  • 01 Aug, 2021
  • 291 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

myelosuppressive chemotherapy
cancer
tumor markers
solid tumour
donor lymphocyte infusion
  • 997 views
  • 01 Aug, 2021
  • 114 locations
Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma

Background Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. Two types are embryonal RMS (ERMS) and alveolar RMS (ARMS). Dasatinib may

cancer chemotherapy
monoclonal antibodies
growth factor
soft tissue sarcoma
cancer
  • 246 views
  • 01 Aug, 2021
  • 2 locations
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

, rhabdomyosarcoma and other soft tissue sarcoma and to measure the length of time during and after treatment that their disease does not get worse. Researchers also want to find out if nab-paclitaxel combined with

myelosuppressive chemotherapy
hematopoietic growth factors
growth factor
cancer
ewing's sarcoma
  • 146 views
  • 21 Jul, 2021
  • 15 locations
Dose Escalation Study of CLR 131 in Children Adolescents and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma Rhabdomyosarcoma Ewings Sarcoma and Osteosarcoma

The study evaluates CLR 131 in children, adolescents, and young adults with relapsed or refractory malignant solid tumors and lymphoma and recurrent or refractory malignant brain tumors for which there are no standard treatment options with curative potential.

karnofsky performance status
iobenguane
lymphoma
positron emission tomography
cancer
  • 160 views
  • 01 Aug, 2021
  • 5 locations
SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes

Although regorafenib was approved for use in patients who had progressive GIST despite imatinib and/or sunitinib on the basis of phase II and phase III data, it has not been examined in a systematic fashion in patients with other forms of sarcoma. Given the activity of sorafenib, sunitinib and pazopanib …

small molecule
growth factor
ewing's sarcoma
pazopanib
systemic therapy
  • 150 views
  • 21 Jul, 2021
  • 17 locations
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy

This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.

spinal cord
peripheral neuropathy
cancer
  • 120 views
  • 01 Aug, 2021
  • 2 locations
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Patients may be considered if the cancer has come back, has not gone away after standard treatment or the patient cannot receive standard treatment. This research study uses special immune system cells called AGAR T cells, a new experimental treatment. The body has different ways of fighting infection and disease. …

cytoxan
platelet count
cancer chemotherapy
ap1903
schwartz
  • 0 views
  • 29 Jul, 2021
  • 1 location