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Glaucoma Clinical Trials

A listing of Glaucoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (184) clinical trials

Evaluation of Safety and Efficacy of Brimonidine Tartrate Ophthalmic Suspension

The study will be conducted to evaluate the efficacy and safety of topical administration of brimonidine tartrate ophthalmic suspension compared with brimonidine tartrate ophthalmic solution.

Phase

Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic

Upon discharge from hospital for COVID-19 infection (or during a telephone call for patients already discharged at the start of the study), patients will be informed of the study. An ophthalmology appointment will be given to them between 4 and 6 months after their discharge. During the ophthalmology appointment, the …

Phase N/A

A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments

The purpose of this study is to evaluate the efficacy of ustekinumab in participants with active polymyositis (PM)/dermatomyositis (DM) despite receiving 1 or more standard-of-care treatments (for example, glucocorticoids and/or immunomodulators).

Phase

Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease

The purpose of this study is to explore the safety, tolerability and activity of Nivolumab, a PD-1 inhibitor, in cohorts of patients with autoimmune disease. Two cohorts of patients will be enrolled, based on autoimmune disease type as outlined below. Entry into cohorts 1 and 2 will start simultaneously and …

Phase

Study of the Beacon Aqueous Microshunt in Patients With Refractroy Glaucoma

This is a prospective, multicenter, single-arm clinical study to evaluate the safety and effectiveness of Beacon Aqueous Microshunt in patients with refractory glaucoma.

Phase N/A

Perfecting Refraction in India With Superior Service Models

Background Need: The leading cause of vision impairment among children in India, and in the world more widely, is an uncorrected refractive error (URE). For example, the population-based Refractive Error Studies in Children (RESC) studies found that 61% of vision impairment in rural children and 89% in urban children in …

Phase N/A

Village-Integrated Eye Worker Trial II

The research will consist of a large cluster-randomized trial in Nepal in which all communities receive visual acuity screening during a baseline census, and then half subsequently receive screening with OCT and intraocular pressure testing with an iCare tonometer. Participants with abnormal results will be referred to the local eye …

Phase N/A

Trial to Evaluate Efficacy and Safety of Lenabasum in Dermatomyositis

Subjects will be randomized to receive lenabasum 20 mg twice per day, lenabasum 5 mg twice per day, or placebo twice per day in a 2:1:2 ratio. The primary efficacy outcome at Week 52 will be Total Improvement Score (TIS), which is a weighted composite measure of improvement from baseline …

Phase

A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma

Participants will engage in baseline, intervention, post-intervention, and follow-up visits over the span of approximately 8 weeks. The expected outcomes for this project are that (1) rtACS activates viable but poorly or non-functional retinal ganglion cells to improve their structural and functional capabilities, (2) measures of retinal, optic nerve, and …

Phase N/A

Village-Integrated Eye Worker Trial II - Pilot

Specific Aim 1: to determine whether screening leads to increased visual acuity compared to the cataract camp approach. Specific Aim 2: to determine whether a community health volunteer program increases the rate of cataract surgery compared to a no program.

Phase N/A