Heart Transplantation Clinical Trials

A listing of Heart Transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 103 clinical trials
Clinical Laboratory Evaluation of Chronic Autonomic Failure

get up. They have had a heart transplant or bilateral endoscopic thoracic sympathectomies or have had or will have renal sympathetic ablation Design

heart transplant
sympathectomies
pure autonomic failure
hypertension
cardiac symptoms
  • 93 views
  • 01 Aug, 2021
  • 1 location
New Horizons for the Treatment of Cardiomyopathy in Children

Collecting mono nuclear cells from the patient's blood after a course of granulocyte stimulation then injecting them into the weak heart muscle measuring the heart function at the beginning and after 2.4.6 months to assess the improvement due to this procedure, by comparing these patients to patients with the same …

cardiomyopathy
dilated cardiomyopathy
heart failure
  • 0 views
  • 25 Aug, 2021
  • 1 location
Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

Researchers want to better understand what happens to the heart when the stem cells are injected directly into the muscle of the right side of the heart during the Stage II palliative surgery for single ventricle patients with hypoplastic left heart syndrome (HLHS) or HLHS variant. Researchers want to see …

hlhs
single ventricle
  • 12 views
  • 27 May, 2021
  • 10 locations
Swedish Evaluation of Left Ventricular Assist Device as Permanent Treatment in End-stage Heart Failure

The study is a prospective, randomized, non-blinded, national, multi-center study. The study will consist of the assignment of eligible patients to treatment with either a HeartMate III (HM III) left ventricular assist device system or to pharmacological treatment (optimal medical management, OMM) according to current guidelines. Eighty (80) patients will …

  • 2 views
  • 23 Jan, 2021
  • 11 locations
Renal Sympathetic Denervation for Patients With Chronic Heart Failure

To study whether renal sympathetic denervation(RSD) RSD can slow the progression of CHF and reduce the rate of all-cause mortality effectively and securely.

ejection fraction
  • 0 views
  • 07 Nov, 2020
  • 1 location
Intracoronary Analysis of Cardiac Allograft Vasculopathy by Means of Optical Coherence Tomography

Randomized prospective multi-center imaging study which investigates the impact of different immunosuppressive protocols (Everolimus (Certican) or Mycophenolate mofetil (CellCept)) on cardiac allograft vasculopathy (CAV) in heart transplanted patients. Maximal intima-thickness will be visualized by optical coherence tomography (OCT) to assess the progression of CAV.

immunosuppressive agents
cellcept
heart transplantation
everolimus
mycophenolate
  • 1 views
  • 07 Nov, 2020
  • 1 location
LVAD Conditioning for Cardiac Recovery

The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the …

heart failure
  • 13 views
  • 12 Jun, 2021
  • 1 location
NAN-101 in Patients With Class III Heart Failure

This is a Phase 1, prospective, multi-center, open-label, sequential dose escalation study to explore the safety, feasibility, and efficacy of a single intracoronary infusion of BNP116.sc-CMV.I1c in patients with NYHA Class III heart failure. Patients with symptomatic congestive heart failure will be enrolled until up to 12 subjects have received …

congestive heart failure
heart failure
entresto
ischemic cardiomyopathy
sacubitril/valsartan
  • 17 views
  • 10 Jun, 2021
  • 4 locations
Daily Life Activities in Patients Treated With Continuous-Flow Left Ventricular Assist Devices

Investigation of oxygen uptake during daily life activities in HF patients with and without LVADs.

  • 0 views
  • 27 Feb, 2021
  • 1 location
Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

For fetuses with severe aortic stenosis, in utero balloon aortic valvuloplasty may improve fetal growth of left heart structures and thus improve potential for biventricular repair strategies after birth.

aortic valvuloplasty
stenotic
regurgitation
aortic stenosis
  • 26 views
  • 27 Jan, 2021
  • 1 location