Heart Transplantation Clinical Trials

A listing of Heart Transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 81 clinical trials
Allograft Dysfunction in Heart Transplant

The investigators will evaluate for early evidence of cardiac allograft dysfunction by cardiac MRI and single cell sequencing to determine underlying molecular and macroscopic causes.

  • 0 views
  • 03 Feb, 2022
  • 1 location
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

elimination of these agents. The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant

  • 0 views
  • 19 Jun, 2022
  • 2 locations
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients (ACAV)

Cardiac allograft vasculopathy (CAV) represents the leading cause of late morbidity and mortality in heart transplant recipients as the second most frequent cause of all deaths at 3 years. In

  • 1 views
  • 10 May, 2022
  • 1 location
Angiotensin II as a First-line Vasopressor for Distributive Shock During or After Heart Transplantation or Durable Left Ventricular Assist Device Implantation: A Pilot Study

heart transplant or left ventricular assist device placement will be enrolled. Participants will be randomized to Angiotensin II (Giapreza) vs. placebo plus standard of care, as a first line agent for

  • 0 views
  • 21 Oct, 2022
  • 1 location
Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock (Altshock-2)

heart failure patients with cardiogenic shock, with respect to 60-day survival or successful bridge to heart replacement therapies (heart transplant or Left Ventricular Assist Device implantation).

intraaortic balloon pumping
heart failure
oliguria
hypoperfusion
fluid overload
  • 0 views
  • 22 Mar, 2022
  • 1 location
Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life

The purpose of this study is to: 1) Remodel and restore left ventricular geometry and function. 2) Avoid the need for mechanical circulatory support (MCS) and/or cardiac transplantation (CT). 3

  • 5 views
  • 10 Apr, 2022
  • 1 location
Transplant Renal Artery Stenosis: Observation Versus Stenting - a Feasibility Study (TRASOS)

transplantation, it has long been recognised that rejection can cause narrowing of the heart's blood vessels, and that this complication is the leading cause of heart transplant failure. It is reasonable to

  • 0 views
  • 24 Oct, 2022
  • 1 location
Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS

nevertheless remains a temporary assistance technique pending a potential recovery of cardiac function, or it can be used to direct patients towards a heart transplant or long-term circulatory assistance (Left

chronic heart failure
cernevit
levosimendan
extracorporeal life support
  • 0 views
  • 09 May, 2021
  • 1 location
Impella CP With VA ECMO for Cardiogenic Shock (REVERSE)

including improved end-organ perfusion and possibly improved coronary perfusion, and is a bridge to further therapies including permanent advanced mechanical circulatory support, cardiac transplantation and

heart failure
pulmonary congestion
calcium
inotropic agent
vasopressor
  • 12 views
  • 03 Mar, 2022
  • 1 location