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Depression (Adolescent) Clinical Trials

A listing of Depression (Adolescent) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (33) clinical trials

The Kites research study If your child is affected by depression and still experiencing its symptoms – you may be interested in the Kites study. Kites is an international clinical research study that is looking at the safety and effectiveness of an investigational medicinal product for major depression in children ...

Phase

Clinical trials of Texas, Inc. is conducing a research study for children ages 7-17 who are exhibiting symptoms of depression. Symptoms include sadness, loss of interest in things, feeling like a failure, discouragement and even some suicidal thoughts. Qualified participants receive study-related medical care from a board certified psychiatrist.  

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An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empirically-derived algorithm that specifies whether, when, and how to augment IPT-A. Two ...

Phase

Neural Components Underlying the Treatment of Adolescent Depression

The purpose of the study is to examine the impact of individual cognitive behavioral therapy (CBT) for adolescent depression on neural functioning. Specifically, the study will utilize Brent and Poling's (1997) cognitive behavioral therapy (CBT) manual (Cognitive Therapy Treatment Manual for Depressed and Suicidal Youth), and investigators will examine pre- ...

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Genetic and Neural Predictors of Adolescent Depression

This study aims to examine the relationship between mood and brain activity in adolescent girls in order to better understand the genetic and neural predictors of adolescent depression. The participants in this study will be healthy female adolescents aged 12-14 and their mothers. They will participate for a total of ...

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Neurophysiology Estrogen and Stress Exposure in the Emergence of Depression in Adolescent Girls

Framed within a diathesis-stress model of disease, the primary objective of this research is to determine a pathophysiological role of estradiol (E2) variability in the context of severe psychosocial stress exposure in regulating neurophysiological correlates of affective state change in girls (ages 12-14) during the pubertal transition (i.e., Tanner developmental ...

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Depression & Insulin Sensitivity in Adolescents

There has been rapid escalation of type 2 diabetes (T2D) rates in adolescents. Early-onset T2D (<20y) typically shows a more aggressive course than adult-onset T2D and disproportionately affects girls from disadvantaged, racial/ethnic groups. This group of girls also is at heightened risk for depression, and depression and T2D are linked. ...

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Depression in Adolescents. A Cerebral Structural Diffusion and Functional Magnetic Resonance Imaging Study

Adolescence is a key development period for neurobiological processes underlying emotional and cognitive functions in adulthood. The pathophysiology of mood disorders has recently been associated with maturation changes in brain networks, but little is known on the early brain structure changes associated with depression appearing during this major brain maturation ...

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Therapeutic Drug Monitoring in Child and Adolescent Psychiatry

We aim to analyse in adolescents with mental illness effectiveness, side effects, and serum level concentrations of antipsychotics (olanzapine and aripiprazole), antidepressants (Duloxetine, Atomoxetine) by means of "Therapeutic Drug Monitoring" (TDM) in order to optimize dosage - effect relations and minimize unwanted side effects. Therapeutic drug monitoring is becoming a ...

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Qualitative Evaluation of Therapeutic Alliance in Adolescent Psychiatry

Context: Psychiatric disorders (anorexia nervosa, depression, anxiety based school refusal) are a major public health concern in adolescence. Their treatment is a challenge for the families, the health care system and society. The treatment is complex and non-standardized. In clinical practice, the relational dimension between the stakeholders is recognized by ...

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