Cancer Treatment Clinical Trials

This is a randomized trial to evaluate the clinical benefit of sorafenib 400 mg twice daily and erlotinib 150 mg once a day versus sorafenib 400 mg twice daily and placebo erlotinib once daily in subjects with unresectable advanced or metastatic Child-Pugh A HCC. Patients who are candidates for potentially ...

The objective of this phase-III trial is to compare the efficacy and safety of sorafenib in combination with capecitabine versus capecitabine in combination with placebo in the treatment of subjects with locally advanced or metastatic HER2-negative breast cancer who are resistant to or have failed prior taxane and an anthracycline ...

The MR-guided ExAblate Focused Ultrasound study is being conducted to assess the safety and effectiveness of an investigational device for the treatment of prostate cancer. The ExAblate treatment is a focal treatment where a small portion of the prostate is treated, only where the cancer is located. The study will ...

The BWEL Breast Cancer Weight Loss Study will look at whether losing weight, by eating less and exercising more, changes the risk of cancer recurrence in women who have been diagnosed with early breast cancer. The study will enroll more than 3,000 patients with breast cancer in the United States ...

This research study will look at how effective niraparib (a PARP inhibitor) is compared to placebo (a pill with no medicine in it, like a sugar pill) in maintenance therapy for women who have ovarian, fallopian tube or peritoneal cancer, and have responded (complete or partial response) to front-line platinum-based ...

A research study is analyzing blood samples to further the development of cancer screening technologies. This research study may be an option if you: Are at least 18 years of age Meet one of the following criteria: Have been diagnosed with stage IV colorectal cancer Have been diagnosed with IIIB ...

The purpose of this study is to evaluate the safety and tolerability of INCB039110 in combination with osimertinib in subjects with locally advanced or metastatic non-small cell lung cancer (NSCLC).

This is an open label study, active-controlled, multi-center study. The total duration of the study will be approximately 64 months. The screening phase may last up to 30 days. If the results of the procedures done during the screening period allow study participation, there will be randomization into 1 of ...

You are being asked to participate in this study because you have been diagnosed with Polycythemia Vera (PV) and are being actively managed for your PV. PV is a rare blood disease in which your body makes too many red blood cells. The extra red blood cells make your blood ...

You are being asked to take part in this study because you have been diagnosed with cervical cancer which is locally advanced and not suitable for surgery. The alternative to treatment on this trial is to receive standard cisplatin chemotherapy given at the same time as radiation. The purpose of ...