Genitourinary Prolapse Clinical Trials

A listing of Genitourinary Prolapse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 60 clinical trials
A Novel Approach to Posterior Mesh Fixation in Laparoscopic Sacral Colpopexy

This randomized controlled study is designed to test the non inferiority of no attachment of posterior mesh compared to fixation of posterior mesh to the vagina in laparoscopic sacral colpopexy in terms of anatomical correction of the prolapse, post-operative and long term morbidity and rate of recurrence.

brimonidine tartrate ophthalmic solution
incontinence
sacral colpopexy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled Trial

Pelvic organ prolapse (POP) is a common problem among women. Apical prolapse (AP) is a prolapse of the uterus, or vaginal cuff, in women post hysterectomy. Apical fixation to the sacrospinous ligament (SSLF) was first introduced in 1968 by K.RICHTER. .In a large review study, the subjective cure rate after …

brimonidine tartrate ophthalmic solution
hysterectomy
  • 27 views
  • 18 Jul, 2021
  • 1 location
Vaginal Packing After Laparoscopic Sacrocolpopexy

Vaginal packing is used routinely following vaginal reconstructive surgery, however, no recommendation regarding vaginal packing after laparoscopic sacrocolpopexy exists. Despite little data to support the practice, purported benefits better positioning and fixation of the mesh, improving incorporation of the mesh by its fixation and reduced blood loss. Patients often complain …

reconstructive surgery
sacrocolpopexy
brimonidine tartrate ophthalmic solution
discomfort
vaginal packing
  • 30 views
  • 15 Aug, 2021
  • 2 locations
Intraperitoneal and Extraperitoneal Uterosacral Ligament Suspensions for Post-Hysterectomy Vaginal Vault Prolapse

Post-hysterectomy vaginal vault prolapse is a common pelvic floor disorder described as descent of the vaginal apex after hysterectomy. The incidence of post-hysterectomy vault prolapse has been reported to follow 11.6% of hysterectomies performed for prolapse and 1.8% for other benign diseases. The majority of surgical repairs to correct post-hysterectomy …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Enhanced Consent and Preparedness for Surgery Trial

To develop an audiovisual decision aid (AVDA) to improve the informed consent process. The investigators aim to examine the impact of a comprehensible AVDA that is written below the 8th grade reading level. The AVDA would be used for surgical consent compared to traditional verbal consent. Additionally, the investigators plan …

brimonidine tartrate ophthalmic solution
reconstructive surgery
prolapse
incontinence
  • 22 views
  • 24 Feb, 2021
  • 1 location
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery

We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double-blinded randomized clinical trial involving women with pelvic organ prolapse and/or urinary incontinence scheduled to have surgery with the Urogynecologists who comprise the Brigham and Women's …

brimonidine tartrate ophthalmic solution
prolapse
cranberry extract
incontinence
prophylaxis for urinary tract infection
  • 10 views
  • 26 Apr, 2021
Comparison of Two Apical Repair Methods in Women Undergoing Repairs for Prolapse

To date no study has determined prospectively which technique is superior to prevent recurrent Pelvic Organ Prolapse (POP) after vaginal hysterectomy- a major unmet clinical need. The aim of the study is to determine objective anatomical recurrent prolapse after Sacrospinous Ligament Fixation (SLF) vs McCall.

vaginal repair
brimonidine tartrate ophthalmic solution
colporrhaphy
sacrospinous ligament fixation
hysterectomy
  • 1 views
  • 04 Mar, 2021
  • 1 location
The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation

This study will randomize patients to either receive intraoperative administration of local anesthetic and corticosteriod at time of sacrospinous ligament fixation compared to placebo to determine if intraoperative trigger point injection (TPI) improves postoperative gluteal and sciatic pain scores along with use of narcotic pain medications. There is a paucity …

narcotics
local anesthesia
sacrospinous ligament fixation
analgesia
marcaine
  • 26 views
  • 07 Apr, 2021
  • 1 location
Urinary Track Infection Prevention After Urogynecological Surgery

This study is randomized double-blinded placebo-controlled trial to access oral Methenamine Hippurate (MH) in combination with cranberry capsules is superior to cranberry capsules alone in prevention of UTI in patients with transient post-operative urinary retention requiring a Foley catheter after pelvic reconstructive surgery.

reconstructive surgery
prolapse
cranberry extract
brimonidine tartrate ophthalmic solution
methenamine
  • 7 views
  • 11 Mar, 2021
  • 1 location
Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence

This study evaluates the addition of a laparoscopic Burch colposuspension procedure at the time of laparoscopic sacrocolpopexy to prevent stress urinary incontinence. Half of the participants will undergo Burch colposuspension procedure at the time of sacrocolpopexy, and half of the participants will undergo sacrocolpopexy alone.

sacrocolpopexy
brimonidine tartrate ophthalmic solution
incontinence
hysterectomy
stress test
  • 10 views
  • 12 Feb, 2021
  • 2 locations