Genitourinary Prolapse Clinical Trials

A listing of Genitourinary Prolapse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 25 clinical trials
Featured trial
CALGB 90601: A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma

CALGB 90601: A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma

  • 08 Nov, 2020
  • 1 location
LAparoscopic Preventive PRErectal Mesh

Urogenital prolapse is a frequent and invalidating pathology in women, involving the anterior vaginal wall and the uterus in most cases. Posterior vaginal wall prolapse is present in only 50% of cases. Surgery is an option for women with troublesome prolapse. A woman's lifetime risk of undergoing surgery for pelvic …

posterior vaginal wall prolapse
brimonidine tartrate ophthalmic solution
vaginal prolapse
  • 26 Jan, 2021
  • 9 locations
Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Prolapse

This is a single center, investigator initiated study, sponsored by the UZ Leuven, Leuven, Belgium; comparing laser treatment to pelvic floor exercises (PFE). Women with symptomatic prolapse (grade II-IV) who seek for a conservative treatment, with no history of previous POP-surgery will be randomised to either the laser-arm or the …

  • 11 May, 2021
  • 1 location
Evaluation of 3D Translabial Ultrasound Imaging for Pessary Size Estimation

Symptoms of female pelvic floor dysfunction, such as incontinence and pelvic organ prolapse, can be alleviated by using pessaries, which are passive medical devices that are inserted in the vagina to support the pelvic organs. Currently, pessaries are fit through trial and error after manual examination, the accuracy of which …

brimonidine tartrate ophthalmic solution
pelvic organ prolapse
  • 04 Oct, 2022
  • 1 location
Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair

Blepharoptosis (ptosis) repair is a common and generally well tolerated surgical procedure usually performed using local anesthetic. However, a subset of patients appears to experience intraoperative pain/discomfort during ptosis repair using an anterior approach with subcutaneous local anesthetic. Posterior subconjuctival local anesthetic is currently used for eyelid procedures such as …

incision and drainage
ptosis repair
brimonidine tartrate ophthalmic solution
  • 05 Jul, 2022
  • 2 locations
A Comparison of the Effect of Suture Material on Blepharoplasty Incision

The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture. Additionally, the study will assess whether certain Fitzpatrick skin types are associated with increased rates of poor outcomes after blepharoplasty.

Accepts healthy volunteers
  • 27 Apr, 2022
Prospective Long-term Evaluation of the Efficacy and Safety of Calistar S for Transvaginal Pelvic Organ Prolapse Repair (CASPO)

Prospective long-term evaluation of the performance and safety of Calistar S for transvaginal pelvic organ prolapse repair in women with anterior POP with or without apical vaginal involvement

  • 17 May, 2022
  • 6 locations
Comparison of the Efficacy of Sacrocolpopexy, the Amreich-Richter Procedure and Transvaginal Mesh (SAME)

Pelvic organ prolapse, POP, is a common health problem affecting up to 40% of women. Very little is known about the factors associated with surgical failure. Studies have identified a variety of risk factors: younger age, high body mass index and advanced preoperative prolapse (grade III-IV) have been associated with …

body mass index
  • 24 Feb, 2022
  • 1 location
Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial (COMET)

This is a Canadian, multi-centre, double-blind randomized controlled trial of an innovative vaginal surgery technique for correction of pelvic organ prolapse (POP) in women. Vaginal surgery is preferred as minimally invasive, however the investigators do not know if materials such as synthetic polypropylene mesh improve success, durability and cost-effectiveness long-term. …

polypropylene mesh
prolapse repair
vaginal surgery
  • 28 May, 2022
  • 1 location
Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled Trial

Pelvic organ prolapse (POP) is a common problem among women. Apical prolapse (AP) is a prolapse of the uterus, or vaginal cuff, in women post hysterectomy. Apical fixation to the sacrospinous ligament (SSLF) was first introduced in 1968 by K.RICHTER. .In a large review study, the subjective cure rate after …

Accepts healthy volunteers
brimonidine tartrate ophthalmic solution
  • 23 Mar, 2022
  • 1 location