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Diabetes and Hypertension Clinical Trials

A listing of Diabetes and Hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (65) clinical trials

Cooking for Health Optimization With Patients

Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine. It is also the first known longitudinal study to assess the impact of hands-on cooking and nutrition education on patient ...


Enhancing Community Health Through Patient Navigation Advocacy and Social Support

Although non-communicable chronic disease is the leading cause of death in Canada, many patients with chronic diseases do not receive guideline-recommended therapy for a variety of reasons. Lack of awareness of publicly funded programs, financial constraints, personal circumstances, language and cultural barriers make it challenging for patients to follow recommendations. ...

Phase N/A

PCORI Integrated Care (IC) Models for Patient-Centered Outcomes

Study aims. Given the documented need for valuable information about system-level features that can be used to effectively and efficiently support adults in living well with MCC, this study is designed to achieve the following aims: Aim 1: Compare the effectiveness of High-Touch, High-Tech, and Usual Care on primary outcomes ...

Phase N/A

Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care In Kisarawe Tanzania

This study focuses on the integration of HIV and NCD screening and care. The investigators will conduct a randomized controlled trial examining the efficacy and cost-effectiveness of the intervention strategy in Kisarawe District, Tanzania, a rural area 40 KM southwest of Dar es Salaam. The study will match two similar ...

Phase N/A

Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes Dyslipidemia and Hypertension

TRC150094 is an Investigational Product for the treatment of CV risk associated with non-traditional risk factors ie, diabetes, hypertension and dyslipidemia, which acts by increasing the energy expenditure and restoring mitochondrial flexibility which is deranged in patients with these risk factors. Treatment with TRC150094 has shown clinically meaningful benefits in ...


Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition

This study will test the hypothesis that neprilysin inhibition with sacubitril/valsartan will increase endogenous glucagon-like peptide-1 (GLP-1) after a mixed meal compared to valsartan. The primary statistical analysis will be within subject comparison (paired t-test or nonparametric equivalent) of area under the curve intact GLP-1 after the meal during sacubitril/valsartan ...


Health Outcomes of Patients With Stable Chronic Disease Managed With a Healthcare Kiosk

Patients who seek primary healthcare vary in their time and resource requirements. Patients with acute medical conditions or poorly controlled chronic disease typically require more time and attention compared to patients with stable chronic disease. Patients with chronic disease routinely make follow-up visits to their primary care provider for assessment ...

Phase N/A

Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors (GliRACo 1)

The pathophysiological explanations of the cardiovascular improvement of patients treated with SGLT2i are not yet known: osmotic diuresis and natriuresis, direct effects of weight reduction, increased in nitric oxide release, oxidative stress reduction, local renin-angiotensin-aldosterone system (RAAS) inhibition are the supposed mechanism. In the Literature the diuretic effect of SGLT2i ...

Phase N/A

Intervention for High-normal or Borderline-elevated Blood Pressure in Adults With Type 2 Diabetes

The IPAD trial is a randomized, double-blind, placebo-controlled, multicenter study. 12,000 patients will be recruited over three years with a median follow up of 3.5 years. IPAD tests the hypothesis that antihypertensive medical therapy in adult patients with type 2 diabetes, whose seated BP ranges from 130 to 149 mm ...


Dissemination of the Cardiovascular Risk Service

Cardiovascular disease (CVD) causes 2,200 deaths in Americans every day with one death every 39 seconds. Yet effective implementation of research-based interventions that reduce CVD-related illness and death remains a substantial challenge. The objective of this study is to test the scalability of a pharmacist-led, remote CVD risk and prevention ...

Phase N/A