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Diabetes and Hypertension Clinical Trials

A listing of Diabetes and Hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (575) clinical trials

Treatment of Brain AVMs (TOBAS) Study

Intracranial arteriovenous malformations (AVMs) are relatively uncommon but increasingly discovered lesions that can lead to significant neurological disability or death.1 Population-based data suggest that the annual incidence of discovery of a symptomatic AVM is approximately 1.1 per 100 000 population.7. AVMs commonly present following an intracranial hemorrhage or seizure, although …

Phase N/A

Genetics of Type 2 Diabetes in West Africans

This research protocol is designed to study the genetic basis of Type 2 Diabetes (T2D) and related conditions in Africa. This project, the Africa America Diabetes Mellitus (AADM) Study, has been continuously funded for over a decade by multiple institutes at NIH including an R01 grant from the NIDDK to …

Phase N/A

UroCCR Database: French Research Network for Kidney Cancer

The UroCCR database is a national medico-scientific network focused on therapeutic management and applied research in kidney cancer. Secondary objectives: - Evaluate and compare different surgical approaches in the treatment of kidney cancer, - Evaluate and compare safety/efficacy of different drugs in the treatment of kidney cancer.

Phase N/A

Evaluation of OZURDEX in Patients With Macular Edema Secondary to Retinal Vein Occlusion in China

This study will take place in China to evaluate the safety and efficacy of OZURDEX implant 700 g in the treatment of macular edema due to retinal vein occlusion (RVO) in patients who have never received treatment for RVO.

Phase

Search for New Methods to Detect Acute Renal Failure

The mortality of acute renal failure (ARF) remains high despite advances in supportive care. There are no established effective drug therapies, and dialysis may promote renal injury via hypotension or neutrophil activation. Many agents [e.g., mannitol, furosemide, dopamine, Atrial Natrieuretic Peptide (ANP), Insulin-like Growth Factor (IGF-1), thyroid hormone, etc.] are …

Phase N/A

Chinese Herbal Medicine and Micronized Progesterone for Live Births in Threatened Miscarriage

The causes of spontaneous miscarriage are diverse and comprise chromosomal, genetic, anatomical, immunological, hormonal, infectious and psychological factors, the other factors contribute to an increased risk include advancing paternal and maternal age and mothers with systemic diseases, such as diabetes or thyroid dysfunction. However, the incidence is difficult to determine …

Phase

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Background Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare autosomal dominantly inherited disorder which confers susceptibility to develop cutaneous and uterine leiomyomas and renal cell carcinoma. HLRCC is caused by mutations in the Krebs cycle enzyme, fumarate hydratase localized on chromosome 1q42.3-q43. Objectives Define the risk of developing …

Phase N/A

Evaluation of Intestinal Microbiota Manipulation to Treat Resistant Hypertension

The gastrointestinal tract begins its colonization shortly after the birth. During the first two years of life, microbiota is unstable and less diverse than in adulthood, when its complexity and diversity are modified. There are more than 100 trillion microorganisms hosted in the gut, mostly as phylae, Bacteroidetes and Firmicutes. …

Phase N/A

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

The National Institutes of Health (NIH)-sponsored collaborative APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) is charged with prospectively assessing the effects of renal-risk variants (RRVs) in the apolipoprotein L1 gene (APOL1) on outcomes for kidneys from donors with recent African ancestry and the recipients of their kidneys, after deceasedand living-donor …

Phase N/A

A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer

Background Papillary RCC is the second most common histologic subtype of kidney cancer, accounting for approximately 10-15% of cases Type 1 papillary RCC occurs in both sporadic and hereditary forms, which are histologically identical. Non familial type 1 papillary RCC can present as both solitary renal tumors and as bilateral, …

Phase