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Diabetes and Hypertension Clinical Trials

A listing of Diabetes and Hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (474) clinical trials

The primary objective of this study will be to evaluate the effect of EQW, used in addition to the current usual care for glycemic control, on major macrovascular events when administered to patients with type 2 diabetes.

Phase

Dapagliflozin Effect on Cardiovascular Events A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Dapagliflozin 10 mg Once Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischemic Stroke in Patients With Type 2 Diabetes Inclusion Criteria: Provision of informed consent prior to any study specific procedures …

Phase

People with these conditions have a higher risk of heart attack or stroke in the future. Because we know who is at a greater risk, we want to take early steps to try to prevent a cardiovascular emergency. The Aleprevent clinical research study will look at whether an investigational medication …

Phase N/A

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase 3 Trial to Evaluate the Safety and Efficacy of xxxxxxxxx in Subjects with Type 2 Diabetes with Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor (ACEI) or Angiotensin Receptor Blocker (ARB) Patient Inclusion Criteria: Subjects must be willing and able to give …

Phase

A 8 to 12 Week Randomized, Double-Blind Study to Compare the Fixed-Dose Combination of Telmisartan 80 + Amlodipine 10mg Versus Amlodipine 10mg Monotherapy as First Line Therapy in Type 2 Diebetes Patients with Hypertension (High Blood Pressure) Patient Inclusion Criteria: Men or Women 18 Years of Age or Older May …

Phase

9-ING-41 in Patients With Advanced Cancers

9-ING-41 is a first-in-class, intravenously administered, maleimide-based small molecule potent selective GSK-3 inhibitor with significant pre-clinical antitumor activity. GSK-3 is a serine/threonine kinase initially described as a key regulator of metabolism and has a role in diverse disease processes including cancer, immune disorders, pathologic fibrosis, metabolic disorders, and neurological disorders. …

Phase

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Background Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare autosomal dominantly inherited disorder which confers susceptibility to develop cutaneous and uterine leiomyomas and renal cell carcinoma. HLRCC is caused by mutations in the Krebs cycle enzyme, fumarate hydratase localized on chromosome 1q42.3-q43. Objectives Define the risk of developing …

Phase N/A

Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical Procedure

Each patient will be examined 4 times: Visit 1 (day -1) collecting and documenting patients' complaints and medical history local examination ultrasound angiography of the lower limbs veins assessment of clinical grade according to CEAP classification Visit 2 (day 0) assessment of venous disease severity according to Venous Clinical Severity …

Phase N/A

Natural History of Stroke: Cause and Development

OBJECTIVE: This is a natural history/disease pathogenesis protocol for evaluation of patients with or at risk for acute stroke, transient ischemic attack (TIA), or other disturbances of cerebrovascular circulation. The purpose of this protocol is to generate natural history data to serve as the basis for future hypothesis-driven protocols as …

Phase N/A

Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome

Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disease consisting of oculocutaneous albinism, a platelet storage pool defect and, in some patients, lysosomal accumulation of ceroid lipofuscin. Other manifestations include pulmonary fibrosis (often fatal in the fourth or fifth decade), chronic granulomatous colitis and, rarely, renal involvement or cardiomyopathy. There …

Phase N/A