Spinal Muscular Atrophy Clinical Trials

A listing of Spinal Muscular Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 63 clinical trials
Histology Study of Biostimulatory Activity of Injectable Poly-L-Lactic Acid (Sculptra Aesthetic)

The study device, Sculptra, is an injectable implant formulation of poly-L-lactic acid microbeads, approved by the FDA for treatment of facial fat loss (lipoatrophy of HIV disease). It is being used off-label by dermatologists to treat dermal defects, as a biologically active filler. Anecdotal evidence suggests that subjects' skin quality …

  • 0 views
  • 19 Aug, 2021
  • 1 location
Motor Imagery Training in Community Dwelling Elderly

An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation. Age has a detrimental effect on the physical performance and the muscle strength, the reduced muscle strength, mass and structure in the elderly …

  • 0 views
  • 11 Sep, 2021
  • 1 location
A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

The purpose of this study is to evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. The investigational treatment will be used to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable recovery after peripheral nerve traction and/or crush …

  • 0 views
  • 30 Aug, 2021
  • 1 location
Transcranial Magnetic Stimulation and Tobacco Use Disorder

The purpose of this study is to determine if brain stimulation using repetitive transcranial magnetic stimulation (rTMS) directed at different parts of the brain can decrease feelings of cigarette craving and symptoms of cigarette withdrawal, and also if men and women have different responses to rTMS. Participants will visit the …

brain stimulation
smoke tobacco
diabetes
cancer
tobacco smoke
  • 0 views
  • 23 Nov, 2021
  • 1 location
SVF (Adipose Tissue Derived MSC) Based Therapy for CKD.

To assess the safety of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease. To assess the efficacy of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease.

nephropathy
glomerular filtration rate
  • 6 views
  • 24 Jan, 2021
  • 1 location
Observational Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

The primary objective is to evaluate the safety of nusinersen sodium injection in the postmarketing setting in Korea. The secondary objective is to evaluate the effectiveness of nusinersen sodium injection in the postmarketing setting in Korea.

nusinersen
spinraza
  • 7 views
  • 04 Apr, 2021
  • 14 locations
Non-Interventional Postmarketing Surveillance Study of Nusinersen Sodium Injection

The primary objective of this study is to evaluate the safety of nusinersen sodium injection in the postmarketing setting in China.The secondary objectives are to collect data on the efficacy and the pharmacokinetics of nusinersen sodium injection in the post-marketing setting in China.

nusinersen
  • 0 views
  • 31 May, 2021
  • 9 locations
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and

  • 94 views
  • 22 Oct, 2021
  • 72 locations
Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA)

The SMA REACH UK Network is a national and international partnership between doctors and therapists involved in the care of children and adults with Spinal Muscular Atrophy. This network is

muscle atrophy
neuromuscular diseases
  • 4 views
  • 05 Jul, 2021
  • 1 location
A Registered Cohort Study on SMA

Spinal muscular atrophy (SMA) is an autosomal recessive disease that causes progressive muscle wasting and weakness due to loss of motor neurons in the spinal cord. This is a registered cohort

  • 0 views
  • 23 Jan, 2021
  • 1 location