Spinal Muscular Atrophy Clinical Trials

A listing of Spinal Muscular Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 34 clinical trials
Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis

The objective of this trial is to assess the efficacy and safety of CNM-Au8 as a remyelinating treatment for vision-impairing MS lesions in participants who have chronic vision impairment as a result of Relapsing-Remitting Multiple Sclerosis. The primary endpoint is to assess the efficacy and safety of CNM-Au8 as a …

deficit
diabetic retinopathy
disease or disorder
relapsing multiple sclerosis
  • 39 views
  • 09 May, 2021
  • 17 locations
NuroSleeve Powered Brace to Restore Arm Function

The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one arm sufficient to perform daily activities. This study could lead to …

neurological disorder
spasticity
range of motion
weakness
Accepts healthy volunteers
  • 0 views
  • 17 Oct, 2021
  • 1 location
A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

The purpose of this study is to evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. The investigational treatment will be used to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable recovery after peripheral nerve traction and/or crush …

  • 0 views
  • 30 Aug, 2021
  • 1 location
Observational Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

The primary objective is to evaluate the safety of nusinersen sodium injection in the postmarketing setting in Korea. The secondary objective is to evaluate the effectiveness of nusinersen sodium injection in the postmarketing setting in Korea.

spinraza
nusinersen
  • 7 views
  • 04 Apr, 2021
  • 14 locations
Non-Interventional Postmarketing Surveillance Study of Nusinersen Sodium Injection

The primary objective of this study is to evaluate the safety of nusinersen sodium injection in the postmarketing setting in China.The secondary objectives are to collect data on the efficacy and the pharmacokinetics of nusinersen sodium injection in the post-marketing setting in China.

nusinersen
  • 0 views
  • 31 May, 2021
  • 9 locations
French Register of Patients With Spinal Muscular Atrophy

The primary objectives of the study are to obtain clinically meaningful data on survival and outcomes of all the patients with spinal muscular atrophy (SMA) 5q types 1 through 4 (according to

muscle atrophy
  • 0 views
  • 21 Feb, 2021
  • 2 locations
Prospective Evaluation of Infants With Spinal Muscular Atrophy:

SPOT SMA is a prospective NIH-supported clinical study targeting pre-symptomatic or recently diagnosed infants and children with Spinal Muscular Atrophy (SMA) types 1, 2, or 3 and their healthy

muscle atrophy
  • 28 views
  • 25 Jan, 2021
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and

  • 94 views
  • 22 Oct, 2021
  • 72 locations
Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA)

The SMA REACH UK Network is a national and international partnership between doctors and therapists involved in the care of children and adults with Spinal Muscular Atrophy. This network is

neuromuscular diseases
muscle atrophy
  • 4 views
  • 05 Jul, 2021
  • 1 location
A Registered Cohort Study on SMA

Spinal muscular atrophy (SMA) is an autosomal recessive disease that causes progressive muscle wasting and weakness due to loss of motor neurons in the spinal cord. This is a registered cohort

  • 0 views
  • 23 Jan, 2021
  • 1 location