Gambling Problems Clinical Trials

A listing of Gambling Problems medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 95 clinical trials
A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study

The purpose of this study is to assess the long-term safety of selexipag while providing continued selexipag treatment for participants who were previously enrolled in an Actelion-sponsored study with selexipag and who derived benefit from selexipag in indications for which a positive benefit-risk has been established.

  • 0 views
  • 12 Sep, 2021
  • 15 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

cardiopulmonary exercise testing
stress test
diuretics
endothelin receptor antagonist
ralinepag
  • 0 views
  • 22 Sep, 2021
  • 32 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

arginine
digoxin
beta-blocker
endothelin receptor antagonist
right heart catheterization
  • 5463 views
  • 24 Sep, 2021
  • 308 locations
ABI-009 an mTOR Inhibitor for Patients With Severe Pulmonary Arterial Hypertension

mTOR activation has been shown to be relevant in the development and progression of pulmonary hypertension. Inhibition of mTOR has been shown to reverse or regress pulmonary hypertension in animal models. ABI-009 is an albumin-bound mTOR inhibitor with improved penetration in lung tissue.

congenital heart defects
left ventricular end-diastolic pressure
pulmonary arterial hypertension
primary pulmonary hypertension
pulmonary function test
  • 1 views
  • 27 Feb, 2021
  • 6 locations
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g). Based on the current numbers of VLBW infants born annually in the U.S., between 5,000-10,000 neonates will develop BPD each year. It is estimated that 8-42% of …

pressure support
citrulline
pulmonary disease
FIO2
very low birth weight
  • 0 views
  • 26 Jan, 2021
  • 1 location
Catheter Ablation of Atrial Fibrillation in Patients With Pulmonary Hypertension Hypertension: a Randomised Study

Atrial fibrillation (AF) and atrial tachycardia (AT), including type I atrial flutter, are frequently observed in patients with pulmonary hypertension (PH). Catheter ablation of AF / AT has been established as an effective treatment option in selected patients. However, little is known about the efficacy and safety of this approach …

catheter ablation
atrial flutter
arrhythmia
  • 0 views
  • 23 Jan, 2021
  • 3 locations
Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension

In a group of patients with PAH treated with treprostinil, the current study aims to investigate the effect of treatment on RV structure and function; and correlate changes in RV structure and function with: World Health Organisation (WHO) class, Six-minute walk test, Quality of life (QoL), and Pre-specified biomarkers (N-terminal …

nesiritide
endothelin receptor antagonist
right heart catheterization
endothelin
pulmonary arterial hypertension
  • 9 views
  • 23 Jan, 2021
  • 1 location
Acute Decompensation of Pulmonary Hypertension

The main objective of this study is to analyze the survival of a cohort of patients admitted for acute decompensation of pulmonary arterial hypertension or postembolic pulmonary hypertension and to establish the prognostic value of biomarkers.

pulmonary arterial hypertension
diuretics
chronic thromboembolic pulmonary hypertension
diuretic therapy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Training Single Arm

The pulmonary hypertension is a disease, which tends to a progredient right heart failure. Although there was a large progress in development of medical therapy, the quality of life, the physical efficiency and the prognosis of the patients are still limited. The aim of the study is to examine the …

right ventricular failure
right heart catheterization
heart failure
  • 1 views
  • 10 May, 2021
  • 1 location
Effect of Exercise and Respiratory Therapy on Right Ventricular Function in Severe Pulmonary Hypertension

Chronic pulmonary hypertension (PH) is associated with impaired exercise capacity, quality of life and right ventricular function.The disease is characterized by an increase of pulmonary vascular resistance and pulmonary arterial pressure, leading to right heart insufficiency. In later stages of the disease, the right heart is not able to further …

pulmonary arterial hypertension
right heart catheterization
heart failure
pulmonary arterial pressure
  • 7 views
  • 11 May, 2021
  • 1 location