Allergies & Asthma Clinical Trials

A listing of Allergies & Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 216 clinical trials
Evaluation of the Response to Monoclonal Antibody Therapy in Severe Asthma: Research of Predictive Biomarkers in Exhaled Air

This study evaluates the change in the composition of Volatil Organic Compounds (VOC) in patients treated by monoclonal antibody for severe asthma.

  • 3 views
  • 21 Feb, 2021
  • 2 locations
The Effect of NAC on Lung Function and CT Mucus Score

This study evaluates 20% n-acetylcysteine (NAC) in the treatment of moderate-to-severe asthma that is complicated by mucus in the airway, as determined by CT imaging. The study is a crossover design, which means that half the study participants will get 20% NAC in the first 14-day treatment period and placebo …

pulmonary function test
methacholine
spirometry
bronchodilator
obstruction
  • 22 views
  • 14 May, 2021
  • 1 location
Study to Evaluate Tezepelumab in Adults With Severe Uncontrolled Asthma

A Regional, Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults with Severe Uncontrolled Asthma

fluticasone
albuterol
  • 29 views
  • 22 Jun, 2021
  • 56 locations
A Study of Itolizumab (EQ001) to Evaluate the Safety Tolerability PK PD and Clinical Activity in Uncontrolled Asthma

This is a multi-center study to evaluate the safety, tolerability, PK, PD, and clinical activity of itolizumab (EQ001) in subjects with moderate-to-severe asthma.

fluticasone
forced expiratory volume
albuterol
anticholinergics
  • 634 views
  • 02 Mar, 2021
  • 13 locations
A Study of MRx-4DP0004 in Asthma

This is a multicentre, phase I/II, double-blind, placebo-controlled study of MRx-4DP0004 in participants taking long-term medication for asthma. Participants will take two capsules of MRx-4DP0004 twice daily in addition to their existing asthma medication for 12 weeks. Safety and tolerability and immune modulatory effects of MRx-4DP0004 will be assessed throughout …

  • 278 views
  • 19 Sep, 2021
  • 6 locations
Assessing the Expression and the Activity of Rac1 Protein in the Airway Smooth Muscle of Asthmatic Patient

Asthma is a chronic inflammatory respiratory disease affecting 6 to 7% of the French adult population and responsible of 1000 deaths in France every year. Many anti-inflammatory treatments are available but few had been developed to target hyperresponsiveness.Investigators and searchers of the Institut du thorax have recently demonstrated the main …

cough
pulmonary function test
bronchodilator
wheezing
corticosteroids
  • 0 views
  • 08 Apr, 2021
  • 1 location
Efficacy and Safety Study of Dupilumab in Patients With Persistent Asthma

Primary Objective: To evaluate the efficacy of dupilumab in patients with persistent asthma Secondary Objectives: To evaluate the safety and tolerability of dupilumab To evaluate the effect of dupilumab on improving patient reported outcomes including health related quality of life To evaluate dupilumab systemic exposure and immunogenicity

prednisone
fractional exhaled nitric oxide
eosinophil count
nitric oxide
bronchodilator
  • 128 views
  • 16 Mar, 2021
  • 69 locations
Corticosteroids/ 2-agonists in Hair in Asthmatic Patients (CorticHair)

This feasibility study will be open-label with two dose groups: patients receiving budesonide/formoterol Turbuhaler at a total daily dose [400 to 800 g[ (group 1) and patients receiving a total daily dose 800 g/day (group 2) to investigate whether there is a relationship between dose and hair concentration. The objective …

budesonide
corticosteroids
formoterol
  • 4 views
  • 29 Jan, 2021
  • 1 location
Vaginal Microbiome Exposure and Immune Responses in C-section Infants

The purpose of this research study is to assess at how differences in the microbiome (naturally occurring bacteria) of a baby may protect, or put a baby at risk, for allergic problems. The microbiome refers to the thousands of bacteria and molds that live in and on our bodies. The …

allergic asthma
atopy
  • 6 views
  • 19 Sep, 2021
  • 2 locations
An Exploratory Study to Characterise Changes in Airway Inflammation Symptoms Lung Function and Reliever Use in Adult Asthma Patients

This is a randomised, active-comparator, open-label, parallel-group, multicentre phase IV exploratory study to characterise changes in airway inflammation, symptoms, lung function, and reliever use in asthma patients using SABA (salbutamol) or anti inflammatory reliever (SYMBICORT) as reliever medication in addition to SYMBICORT as daily asthma controller. Eligible patients diagnosed with …

pulmonary function test
fractional exhaled nitric oxide
spirometry
maintenance treatment
symbicort
  • 38 views
  • 17 Sep, 2021
  • 6 locations