Allergies & Asthma Clinical Trials
A listing of Allergies & Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 115 clinical trials
High Flow Nasal Cannula in Children With Status Asthmaticus (CANULASTHM)
In France, over 2.5 million people suffer from asthma, including one-third of children. This is the chronic respiratory disease leading to the highest rate of hospitalization. The conventional oxygen delivery means in children are the non-rebreather face mask or low flow nasal cannula (standard oxygen therapy - SOT). New non-invasive …
- 27 views
- 04 Oct, 2022
- 14 locations
Role of "Asthma School" in Disease Management
. According to the definition provided by the GINA guidelines, asthma is characterized by a variable and reversible limitation of expiratory airflow and by the following symptoms: wheezing, dyspnoea, thoracic constriction and/or cough. The type and the severity of airflow limitation can vary over time (1) depending on external agents, …
- 241 views
- 24 Apr, 2022
- 1 location
Using Technology-Assisted Stepped Care Intervention to Improve Adherence in Adolescents With Asthma (TASC)
To test the preliminary efficacy of the TASC adherence promotion intervention for adolescents with asthma in a feasibility randomized controlled trial compared to treatment as usual control arm.
- 0 views
- 05 Mar, 2022
- 1 location
Increased Lung Volume as Controller Therapy for Asthma
This is an early phase clinical trial to test the efficacy of elevating lung volume with positive expiratory pressure (CPAP) as a controller therapy for asthma in patients with a BMI ≥ 30 kg/m2. There will be two phases to this trial. Phase I: In the first phase we will …
- 13 views
- 15 Jun, 2022
- 1 location
Small Airway Inflammation and Dysfunction in Different Asthma Phenotypes
Small airway inflammation and dysfunction will be measured in 40 children and 40 adults with asthma before and after 8 weeks of treatment with inhaled budesonide. The same measurements will be conducted once in 80 age and sex matched healthy controls.
- 0 views
- 28 Oct, 2021
- 1 location
Phosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe Asthma
This study evaluates the effects of roflumilast on restoring response β2 adrenoreceptor agonists in low T2, obese asthmatics. One group of participants will receive roflumilast for 3 months, while the other will receive a placebo.
- 80 views
- 24 Mar, 2022
- 1 location
An Asthma Mobile Intervention to Promote Patient-Reported Outcomes in Primary Care
Through this study, the investigators will adapt the ASTHMAXcel mobile app and evaluate the adapted intervention through a randomized controlled trial.
- 12 views
- 19 Jun, 2022
- 1 location
A Clinical Study to Test the Safety, Exposure, and Pharmacodynamic Markers of CSL311 in Patients With Mild Asthma and in Healthy Volunteers
This is a phase 1, first-in-human (FIH), multi-center, randomized, double-blind, placebo-controlled study of CSL311 in patients with mild asthma. The primary objective of this study is to assess the safety and tolerability of single ascending doses (SAD) and multiple ascending doses (MAD) of CSL311.
- 42 views
- 23 Apr, 2022
- 2 locations
AIM2ACT: A Mobile Health Tool to Help Adolescents Self-Manage Asthma (AIM2ACT)
The aim is to test the efficacy of AIM2ACT and long-term maintenance of treatment effects in a fully-powered randomized controlled trial with 160 early adolescents with poorly controlled persistent asthma, ages 12-15 years, and a caregiver
- 0 views
- 11 Jul, 2022
- 1 location
Preventing Asthma in High Risk Kids (PARK)
This trial is a randomized, double-blind, placebo controlled trial designed to test whether two years treatment of preschool children aged 2-3 years of age at high risk for asthma with omalizumab (anti-IgE) for two years will prevent the progression to childhood asthma, as reflected by a reduction in the prevalence …
- 246 views
- 23 Mar, 2022
- 13 locations