Chronic Obstructive Lung Disease Clinical Trials

A listing of Chronic Obstructive Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 265 clinical trials
Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT) (CONVERT)

This is a prospective, open-label, multi-center, single-arm study to be conducted at up to 20 investigational sites. The Study plans to enroll 140 subjects with severe emphysema and collateral ventilation in the target lobe. This protocol is designed to evaluate the utility of the AeriSeal System to occlude collateral air …

lung volume reduction
zephyr
aeriseal
  • 22 views
  • 07 Oct, 2022
  • 12 locations
CHIlled Platelet Study (CHIPS)

A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room

  • 0 views
  • 21 Oct, 2022
  • 15 locations
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical

heart transplant
lupus
heart disease
heart transplantation
coagulopathy
  • 0 views
  • 04 Oct, 2022
  • 12 locations
  • 0 views
  • 07 Oct, 2022
  • 8 locations
Clinical Trial Evaluating External Evaluation and Training on the Incomplete Resection (POLIPEVA Study) (POLIPEVA)

objectives, we will compare the proportion of fragmented polypectomies and adverse events. We will evaluate the factors associated with incomplete excision or failed cold polypectomy, as well as the

colonoscopy
endoscopy
cold
polypectomy
colorectal polyps
  • 0 views
  • 04 Oct, 2022
  • 1 location
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

temperature. Lowering their hand into very cold water. Videos or pictures of the face will recorded while participants get painful stimulation. A test to record heart electrical activity

pain assessment
heat
Accepts healthy volunteers
  • 138 views
  • 28 Oct, 2022
  • 1 location
A Study of Belcesiran in Patients With A1ATD-Associated Liver Disease (ESTRELLA)

This is a multiple dose, randomized, placebo-controlled, double-blind study of belcesiran to evaluate the safety, tolerability, PK, and PD in adult patients with PiZZ A1ATD-associated liver disease. The study will be conducted in 2 parallel cohorts. A total of up to 27 participants may be enrolled in a single cohort. …

alpha1-proteinase inhibitor (human)
  • 2 views
  • 04 Oct, 2022
  • 14 locations
A Clinical Trial of the Use of Remote Heart Rhythm Monitoring With a Smartphone After Cardiac Surgery (SURGICAL-AF 2)

The objective of the study is to evaluate the clinical consequences following the detection of postoperative atrial fibrillation or flutter (POAF) using a remote heart rhythm monitoring strategy with a photoplethysmography based smartphone technology in the early postoperative period after discharge.

diagnostic procedure
fibrillation
coronary artery bypass graft
  • 0 views
  • 04 Oct, 2022
  • 1 location
Tuberculosis (TB) Aftermath

TB Aftermath will compare effectiveness, cost-effectiveness and feasibility of two ACF strategies that are presently being considered by the RNTCP for detecting recurrent TB and provide evidence needed to implement and scale the preferred intervention. The proposed study will address this gap, through the following specific aims: Primary Aim 1: …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device

The purpose of this academic-industrial partnership will be to compare two thermoablation modalities using devices adapted to low and middle income countries (LMICs) to traditional CO2-based cryotherapy for the treatment of cervical precancer. The investigators will investigate whether the cure rates of cervical intraepithelial neoplasia 2 and more severe diagnoses …

cervical intraepithelial neoplasia grade 2
cryotherapy
cervical high grade squamous intraepithelial lesion
cervical dysplasia
cin 3
  • 0 views
  • 04 Oct, 2022
  • 3 locations