Gastrointestinal Diseases and Disorders Clinical Trials

A listing of Gastrointestinal Diseases and Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
Effects of Imagery Therapy vs Progressive Muscle Relaxation Therapy on Patients With Functional Abdominal Bloating

65% of the general population reported experiencing moderate to severe bloating symptoms. Bloating could be disturbing to patients and frustrating to the physicians as an effective treatment is still lacking. Guided Imagery (GI) involves the structured visualisation of mental images with somatic sensories; whereas Progressive Muscle Relaxation (PMR) focuses on …

  • 0 views
  • 19 Mar, 2021
  • 1 location
Effects of Blueberries on Symptoms and Underlying Mechanisms of Functional Gastrointestinal Disorders

There is extensive pre-clinical evidence for potential health effects of blueberries. These are related, but not exclusively due to their high polyphenol content. This translational, clinical, randomized, cross-over, double-blind, placebo-controlled study will investigate the effects of blueberries in freeze-dried powder form on gastrointestinal and extra-gastrointestinal symptoms and function, as well …

  • 0 views
  • 11 Apr, 2021
  • 1 location
PROGRESSive Withdrawal Esomeprazole and Acid-related Symptoms

Rebound acid hypersecretion (RAHS), defined as an increase in gastric acid secretion above pre-treatment levels after PPIs therapy is observed within two weeks after withdrawal of treatment and could theoretically lead to acid-related symptoms such as heartburn, acid regurgitation, or dyspepsia that might result in resumption of therapy. A plausible …

dyspepsia
esomeprazole 40 mg
heartburn
gastrin
rebound phenomenon
  • 1 views
  • 23 Jan, 2021
  • 4 locations
Impact of Stigma on Compliance to Medication in Functional Dyspepsia

To date, no study exists that evaluates whether functional dyspepsia patients experience stigma and how stigma may influence adherence. Thus, the investigators aim to evaluate the relationship between functional dyspepsia and stigma, and explore possible ways to improve treatment adherence.

anxiety
dyspepsia
endoscopy
esophagogastroduodenoscopy
  • 8 views
  • 19 Mar, 2021
  • 1 location
Defining Adolescent Nausea Through Brain Imaging and Neurostimulation Response

This study evaluates the efficacy of auricular neurostimulation via an non-invasive percutaneous electrical nerve field stimulator (PENFS) in adolescents with functional nausea. A neurostimulator is applied to the outer ear and stimulates several nerves that are thought to be involved in transmission of nausea and vomiting signals. Half of the …

nausea
nausea and vomiting
vomiting
  • 9 views
  • 29 Jan, 2021
  • 1 location
Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy

In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.

abdominal surgery
propel
abdominal operation
  • 0 views
  • 23 Jan, 2021
Responses to a Comfort Meal in Functional Dyspepsia

Background. Dyspeptic patients tolerate smaller meal loads than healthy subjects, but it is not known whether and to what extent symptoms relate to abnormal homeostatic or hedonic components of perception. Methods. Parallel studies in patients with symptoms induced by meals (fulfilling Rome IV criteria of postprandial dyspepsia) and sex- and …

dyspepsia
probe
  • 0 views
  • 09 Aug, 2021
  • 1 location
The Gut-Brain Study

The purpose of this study is to find out if transplant of fecal matter (stool), also known as fecal microbiota transplantation (FMT), from a healthy person into the intestines of children and young adults with Autism Spectrum Disorder (ASD). For this study children between the ages of 5-17years will be …

gi symptoms
endoscopy
autism
microbiota
gastroscopy
  • 403 views
  • 24 Jan, 2021
  • 1 location
Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)

Open label interventional randomized pilot study utilizing two dosing regimens of AEMCOLO. The goal of this study is to evaluate effectiveness of a novel antibiotic, AEMCOLO (Rifamycin SV MMX) in the treatment of Small intestinal bacterial overgrowth (SIBO).

aemcolo
small intestinal bacterial overgrowth
  • 2 views
  • 19 Feb, 2021
  • 1 location
Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei

Appendiceal cancer is a rare disease that does not cause many symptoms. As such, doctors are not sure if chemotherapy actually has an effect on the disease. The goal of this clinical research study is to learn more about the effects that chemotherapy may have on appendiceal cancer.

neutrophil count
systemic chemotherapy
cancer
adenocarcinoma
  • 20 views
  • 23 Jan, 2021
  • 1 location