Gastrointestinal Diseases and Disorders Clinical Trials

A listing of Gastrointestinal Diseases and Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 7 clinical trials
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VIVID-1, a clinical research study for adults 18–80 with moderately to severely active Crohn’s disease.

A phase 3 research study of an injectable investigational medicine for adults ages 18 to 80 with moderate to severe Crohn’s disease. Note that study participants may receive the investigational medication, a currently approved Crohn’s medication, or placebo. The study comprises four periods: screening, treatment period 1, treatment period 2, …

gastrointestinal diseases
crohn's disease
gastrointestinal disorder
inflammatory bowel disease
  • 66 views
  • 20 Jul, 2021
  • 74 locations
A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer

Phase Ia - Explore safety and establish the maximum tolerated dose (MTD)/recommended dose levels for phase Ib expansion phase of BI 905711 based on the frequency of patients experiencing dose limiting toxicities (DLTs) during the MTD evaluation period. The MTD evaluation period is defined as the first two treatment cycles …

gastric adenocarcinoma
carcinoma
adenocarcinoma
endoscopic procedures
lipase
  • 74 views
  • 28 Jul, 2021
  • 8 locations
Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas

Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.

carcinoma
adenocarcinoma
KRAS
neutrophil count
platelet count
  • 0 views
  • 25 Jul, 2021
  • 1 location
OH2 Oncolytic Viral Therapy in Solid Tumors

This phase I/II study evaluates the safety and efficacy of OH2 as single agent or in combination with HX008, an anti-PD-1 antibody, in patients with malignant solid tumors (gastrointestinal cancers, head and neck cancers, soft tissue sarcomas). OH2 is an oncolytic virus developed upon genetic modifications of the herpes simplex …

cancer
colony stimulating factor
measurable disease
sarcoma
solid tumour
  • 15 views
  • 31 Jul, 2021
  • 1 location
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

This study will investigate the effects of atezolizumab on select cancer types in people whose analysis of tumour DNA and RNA indicates they may be sensitive to atezolizumab. This study aims to determine if the information from the cancer genome analysis corresponds with the effects of atezolizumab on individuals and …

neutrophil count
platelet count
cancer
g-csf
mammogram
  • 0 views
  • 23 Jul, 2021
  • 1 location
A Study of Gemcitabine Nab-paclitaxel Capecitabine Cisplatin and Irinotecan in Metastatic Pancreatic Cancer

The purpose of this study is to evaluate the clinical activity of gemcitabine, nab-paclitaxel, capecitabine, cisplatin, and irinotecan (GAX-CI) in patients with metastatic pancreatic cancer.

adenocarcinoma
primary cancer
metastatic pancreatic cancer
measurable lesion
gemcitabine
  • 30 views
  • 01 Aug, 2021
  • 1 location
Clinical Utility of WATS3D: A 5-Year Prospective Study

The purpose of this study is to create a registry (collect data and keep it in a research database) to learn more about two methods of taking small tissue samples from your esophagus (the esophagus is the tube that carries food and liquid from your mouth to your stomach). The …

heartburn
dysplasia
acidity
regurgitation
radiofrequency ablation
  • 0 views
  • 01 Aug, 2021
  • 1 location