Peripheral Neuropathy Clinical Trials

This study will see if an investigational drug called NYX-2925 can reduce the nerve pain in the legs and feet associated with painful diabetic peripheral neuropathy.

Suffering from Diabetic Neuropathy? If you suffer from Diabetic Peripheral Neuropathy, also known as DPN, you may be interested in learning more about a research study of an investigational medication being conducted locally.

The objectives of the MEDIAN study are to evaluate the short-term and long-term safety and nutritional benefits of Metanx® versus placebo in subjects with mild to moderate diabetic peripheral neuropathy (DPN). Short-term effects will be evaluated during the first 16 weeks of treatment, and long-term effects will be evaluated over ...

Endeavor Clincial Trials is seeking volunteers to participate in a Diabetic Peripheral Neuropathy (DPN) research study.

The purpose of this study is to evaluate investigational tapentadol extended release (ER) when compared to placebo. Placebo is a dummy pill with no active drug, but looks like the real drug. Tapentadol is an opiod (narcotic) drug. Tapentadol immediate release (IR) has already been approved in does of 50, ...

A research study is evaluating an investigational treatment for chemotherapy induced peripheral neuropathy in patients with colorectal cancer (CRC).

Nerve decompression (ND)as treatment for the foot complications of diabetic sensorimotor peripheral neuropathy (DSPN) is a controversial topic although many patients find it provides gratifying relief of pain and numbness. Neural electrical monitoring has been used intra-operatively to diagnosis nerve abnormality, monitoring for ongoing normal nerve function and confirm nerve ...

The investigators propose to examine the effects of GLP-1 receptor agonist Liraglutide on autonomic sudomotor function and endothelial and neurovascular functions as well as markers of inflammation in patients with type 2 diabetes mellitus (T2DM). The primary objective will be changes in peripheral autonomic function using sudorimetry (Sudoscan) after 1 ...

This is a randomized, placebo-controlled, double-blind, parallel-group clinical trial comparing dextromethorphan and placebo for the treatment of chemotherapy-induced peripheral neuropathy, assessed with a (0-10) numerical scale. Cognition, anxiety, depression, sleep and quality of life are also assessed. The influence of CYP2D6, CYP3A4 and MDR1 polymorphism on the dextromethorphan analgesic efficacy ...

Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety of symptoms including sensation impairments and weakness. The impairments are usually most evident in the feet and ...