Weight Loss Clinical Trials

This study provides the opportunity to compare the traditional duodenal switch to the single anastomosis configuration, allowing the comparison of the traditional duodenal switch data (which has been published and is well known) to the single anastomosis technique. The single anastomosis version of this procedure is technically easier and would ...

The BWEL Breast Cancer Weight Loss Study will look at whether losing weight, by eating less and exercising more, changes the risk of cancer recurrence in women who have been diagnosed with early breast cancer. The study will enroll more than 3,000 patients with breast cancer in the United States ...

Obesity is a growing national health problem that now affects over 35% of Americans and is the leading cause of preventable death. Obesity affects all organ systems and contributes to the cause of a multitude of medical problems such as cardiovascular disease, diabetes and sleep apnea [1]. It is defined ...

The purpose of this study is to compare cardiometabolic health between metabolically-normal and metabolically abnormal obese participants. This study will last up to 1 year. Participants will visit the research center about 8 times before randomization.  The outpatient visits range from less than 1 hour to approximately 6 hours in ...

A Phase IIb, Randomised, Parallel, Double-Blind Placebo-Controlled and Open-Label Active Comparator Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes Mellitus This study is designed to evaluate the dose range for MEDI0382 with respect to blood glucose control ...

Loose watery stool

Researchers at the University of Kentucky are currently enroll ing participants in a research study investigating the effects of strength training on movement patterns and physical function in people with obesity. Participants will perform patterns and physical function will be measured before and after the strength training program.

The overall study will consist of two parts conducted in tandem: This Pilot Study is a 3-month pilot RCT study to test the feasibility of the Sweetch app in combination with a digital body weight scale (DBWS), with both groups receiving usual care for prediabetes.

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study in overweight and obese subjects with CV disease and/or multiple CV risk factors.

The purpose of the trial is to investigate the effect and safety of liraglutide 3.0 mg as an adjunct to intensive behaviour therapy for obesity in a non-specialist setting.