Pulmonary Arterial Hypertension Clinical Trials

A listing of Pulmonary Arterial Hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 156 clinical trials
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions

Pulmonary arterial hypertension (PAH) in patients with congenital heart disease (CHD) is associated with considerable morbidity and even mortality. Next to environmental risk factors, the

early diagnosis
septal defect
hypertension
right heart catheterization
ventricular septal defect
  • 10 views
  • 04 Jun, 2022
  • 1 location
An Open-label, Multi-national, Multi-center, Single-arm, Uncontrolled, Long-term Extension Study of Orally Administered Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension (PAH) Who Received Riociguat in a Bayer Clinical Trial (RIALTO)

To provide riociguat therapy to eligible patients with PAH originating from Bayer-sponsored trials with BAY63-2521/ Riociguat / Adempas® who are currently or recently treated in these trials

adempas
riociguat
pulmonary arterial hypertension
  • 2 views
  • 24 Oct, 2022
  • 1 location
Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension

In a group of patients with PAH treated with treprostinil, the current study aims to investigate the effect of treatment on RV structure and function; and correlate changes in RV structure and

endothelin receptor antagonist
walk tests
rheumatism
endothelin
right heart catheterization
  • 9 views
  • 15 Feb, 2022
  • 1 location
Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart Defects

patients with severe associated pulmonary arterial hypertension (APAH) as part of a congenital heart defect with / without Eisenmenger's Syndrome

apah
congenital heart defects
hypertension
  • 1 views
  • 04 Oct, 2022
  • 1 location
A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial Hypertension

Background High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment, the

hypertension
walk tests
medical therapy
pulmonary function test
spironolactone
  • 11 views
  • 29 Oct, 2022
  • 1 location
Xenon MRI Pulm Hypertension (Jupiter PH)

The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with changes in gas exchange physiology

  • 0 views
  • 05 Jun, 2022
  • 1 location
a Study to Evaluate the Pharmacokinetics and Safety of TPN171H Tablets in Patients With Renal Insufficiency and Healthy Subjects

To evaluate the effect of renal insufficiency on the pharmacokinetics of TPN171H tablets after single dose oral administration, so as to provide basis for formulating clinical medication plan for patients with renal insufficiency; To evaluate the safety of TPN171H tablets in patients with renal insufficiency and healthy subjects

Accepts healthy volunteers
  • 0 views
  • 24 May, 2022
  • 2 locations
Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH (RIVERII)

This is an open-label, single-armed, prospective single-centre clinical study to evaluate the effect of riociguat on right heart size and function in patients with manifest PAH and CTEPH.

  • 0 views
  • 29 Apr, 2022
  • 1 location
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

(dcSSc) or SSc-associated pulmonary arterial hypertension (SSc-PAH).

systemic sclerosis
hypertension
rheumatism
ifetroban
diffuse cutaneous systemic sclerosis
  • 0 views
  • 04 Oct, 2022
  • 11 locations
Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With Right Heart Failure Caused by Pulmonary Arterial Hypertension

Efficacy and safety evaluation of tolvaptan in the treatment of patients with right heart failure caused by pulmonary arterial hypertension

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location