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Lower Back Pain Clinical Trials

A listing of Lower Back Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (156) clinical trials

Evaluating the Role of Neuroinflammation in Low Back Pain

The goal of this research study is to evaluate whether the central nervous systems of those with low back pain are different from those of healthy, pain-free individuals. Specifically, the researchers will test whether "glial cells" (the immune cells of the brain and spinal cord) are more active in patients ...


Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation

Clinical researches has demonstrated the effectiveness of Tuina on lumbar disc herniation (LDH), but the mechanism remains unclear.The existing researches mainly focus on the mechanical mechanism of the local stability reconstruction of the lumbar spine. Our previous study found that LDH patients have lumbar CNS motion control disorder, and preliminary ...

Phase N/A

Clinical Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.

A classification-based approach to identify specific characteristics of patients who seriously suffer from chronic low back pain (CLBP) with referred pain to the legs who are likely to respond to certain interventions has become a research priority in the medical milieu in general and in physical therapy in particularly.While several ...

Phase N/A

PET Patterns Biomarkers and Outcome in Burst SCS Treated FBSS Patients

Background and rationale: Tonic spinal cord stimulation for chronic primarily neuropathic pain har been used for over 50 years. Tonic stimulation in frequencies from 20 to 70 Hz produces analgesia and paresthesia in the targeted area. Burst stimulation, a novel spinal cord stimulation pattern, is an intermittent high frequency parenthesis-free ...

Phase N/A

Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain

Background: Eighty percents of the total population experiences lower back pain (LBP). Prevalence of LBP is about 20 to 30%. LBP is the most frequent disease and causes a lot of the medical and social costs. Recently the traditional drug therapy, exercise therapy has been developed and various non-surgical treatments ...

Phase N/A

Change of Lumbar Symptom After Surgical Treatment for Patients With Cervical Stenosis

The improved back pain score after cervical spinal surgery would be higher than that after non-surgical treatment.

Phase N/A

Yoga vs Stretching in Veterans With Chronic Lower Back Pain: Does Mindfulness Matter?

The study will approach all new or existing patients within the chiropractic clinic between the ages of 18 and 89 who have low back pain greater than 12 weeks and pain greater than or equal to 3, who have no contraindications to active exercise. Patients will be queried as to ...

Phase N/A

The Effect of a Developed Perioperative Rehabilitation Pathway Following Lumbar Arthrodesis

This involves a prospective interventional study with a one year follow-up. The investigators will compare the outcomes of the current rehabilitation pathway with a newly developed (based on systematic review and delphi study) rehabilitation pathway for patients with a single level lumbar arthrodesis. The usual care group (n= 30) will ...

Phase N/A

Assessment of the Efficacy of an Intradiscal Injection of Corticoids in Modic I Discopathies.

This is a randomized, controlled, single-blind with two arms (anaesthetic versus corticoids) trial.


A Trial Comparing Mechanical Diagnosis and Treatment to Manual Therapy

20 new patients entering the chiropractic clinic who meet inclusion criteria including demonstrating a directional preference upon physical examination during their initial evaluation will be recruited. Patients will be queried as to interest and those interested will be consented. Patients will then be randomized utilizing a computer generated randomization chart ...

Phase N/A