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Lower Back Pain Clinical Trials

A listing of Lower Back Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (188) clinical trials

The purpose of this study is to evaluate tanezumab as a treatment for chronic back pain.

Phase

Postmenopausal Osteoporosis is the medical term used for the disease that weakens bones in women, increasing the risk of sudden and unexpected fractures. Literally meaning "porous bone," osteoporosis results in an increased loss of bone mass and strength. The disease often progresses without any symptoms or pain. Many times, osteoporosis ...

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Do you also have constipation? We are conducting a clinical research study that is looking at whether an investigational medication is suitable in treating both moderate to severe chronic low back pain and constipation. Patient Inclusion Criteria You may be able to participate if you: are 18 years of age ...

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Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain Patient Inclusion Criteria: Male and female subjects ≥ 18 years of age with moderate to severe, chronic low back pain (lasting at least several hours daily) as their ...

Phase

Validation of a Treadmill Walking Test to Discriminate Neurogenic Claudication From Vascular Claudication

To date, an important challenge that clinicians hare facing in the assessment and diagnosis of intermittent claudication is that pathologies associated with vascular or neurogenic claudication can coexist in the same patient. Differentiation between both origins can be difficult due to variable signs and symptoms which can be atypical. The ...

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Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain

Subjects will be assessed for pain control and opioid-related side effects following a route of delivery change from systemic opioids to IT morphine therapy.

Phase

Treatment of Hamstring Muscle in Patients With Low-back Pain

Shortening of the hamstrings could be related to low back pain.Therefore, the treatment of these muscles may improve pain. The dry needling technique seems to improve the extensibility of the muscles. This technique seems to be more effective when is applied in the most hyperalgesic areas related to the participant's ...

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Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

The long-term goal of our research agenda is to identify the mechanisms associated with rotator cuff tendinopathy (impingement syndrome) and subsequently evaluate novel treatment strategies that address these mechanisms. The objectives of this application are to study the muscle patterns in patients with rotator cuff tendinopathy as well as the ...

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Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

Vestibulodynia (VBD) is a chronic pelvic pain condition that affects 1 in 6 reproductive aged women, yet remains ineffectively treated by standard trial-and-error approaches. The investigators have identified two distinct VBD subtypes that may benefit from different types of treatment: 1) VBD peripheral (VBD-p) subtype characterized by localized pain specific ...

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Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

A multi-centered, randomized, double-blind, placebo-controlled, two-period cross-over study to compare the safety and efficacy of Omnitram (30 mg to 120 mg daily) and placebo in patients with painful diabetic polyneuropathy. For subjects receiving treatment for neuropathic pain prior to study enrollment, their treatment will be tapered and stopped at least ...

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