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Gastroesophageal Reflux Disease (GERD) Clinical Trials

A listing of Gastroesophageal Reflux Disease (GERD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (88) clinical trials

The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis

Scarring of the lungs is common in patients with scleroderma and is one of the main causes of death. Patients with scleroderma very frequently have problems with their gullet (esophagus), the food pipe that leads into the stomach. Normally, a small circular muscle at the base of the esophagus opens ...

Phase N/A

Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection

The purpose of this study is to evaluate response to non-erosive reflux disease (NERD) treatment between patients with normal endomicroscopy findings compared with patients with abnormal endomicroscopy findings. The researchers will compare two different drug regimens for the NERD subjects to evaluate their effectiveness in reducing NERD-related symptoms. In addition, ...

Phase N/A

Management of Reflux After Sleeve Using Stretta

Gastroesophageal reflux disease (GERD) is a widely prevalent medical disorder in the United States with a spectrum of treatment options ranging from dietary modification, to various pharmacologic treatments, to an array of available surgical and endoscopic procedures. There is a well-described correlation between obesity and symptoms of GERD. The morbidly ...

Phase N/A

The Effect of Non Invasive Electrical Stimulation Therapy on Gastroesophageal Reflux Disease (GERD) Symptoms - Proof of Concept Study

The aims of the study: To evaluate whether the use of a specific TENS technology can improve GERD symptoms and esophageal acid exposure.

Phase N/A

The Primary Symptoms of GERD(Gastroesophageal Reflux Disease) in Chinese Outpatients in Gastroenterology Department

Primary ObjectiveTo define the primary symptom of GERD in Chinese outpatients in Gastroenterology department Secondary Objective1. To investigate the symptom distribution of patients who present with symptoms originated from upper gastrointestinal tract and have pathologic esophageal reflux established by 24-hour impedance-pH monitoring, upper endoscopy, or proton pump inhibitor test. 2. ...

Phase N/A

MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough

The present study has the following objectives: to assess the prevalence of BHR in non-smoking adults with a chronic cough, to assess the prevalence of BHR in patients with UACS and GERD, to evaluate the relationship between BHR and cough reflex sensitivity, to assess the diagnostic accuracy of MCT in ...

Phase N/A

Evaluation of Safety and Effectiveness of the RefluxStop Device in the Management of GERD

Prospective, open-label, multi-centre, single arm treatment only trial to evaluate the safety and effectiveness of RefluxStop for the treatment of GERD. The used medical device "RefluxStop" is an implantable single use sterile device to ensure maintenance of gastro oesophageal junction (GEJ) in an intra-abdominal position to reduce or eliminate GERD. ...

Phase N/A

STRETTA Radio Frequency Ablation (RFA) v/s Sham Therapy for the Treatment of Refractory GERD

Gastro-esophageal reflux disease (GERD) is a chronic disorder with significant impact on the quality of life of patients. It may also lead to several complications like peptic strictures, ulcerations, Barrett 's disease and subsequently adenocarcinoma of the esophagus. Proton pump inhibitors (PPIs) are the mainstay of GERD treatment, with up ...


Registry of Outcomes From AntiReflux Surgery

This is a prospective, multi center, observational database of patients that are having surgical laparoscopic antireflux procedure and/or hiatal hernia repair, including laparoscopic Nissen fundoplication and Magnetic Sphincter Augmentation with the LINX device. Patients meeting registry inclusion and exclusion will be followed for 5 years with standardized quality of life ...

Phase N/A

In Vivo Anatomy Physiology Mechanics and Function of the Lower Esophageal Sphincter

The purpose of this research study is to examine and evaluate a part of the digestive system (gastrointestinal tract). The specific part the study team will look at is called the "lower esophageal sphincter complex." This complex is located where the esophagus (food pipe) meets the top of the stomach. ...

Phase N/A