Gastroesophageal Reflux Disease (GERD) Clinical Trials

A listing of Gastroesophageal Reflux Disease (GERD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 87 clinical trials
The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity

Reflux hypersensitivity is the disease that causes chest pain, heartburn and regurgitation and can impair patients' quality of life. Pain modulators are often used for the treatment of reflux hypersensitivity, but the effect is not enough and more effective therapy is needed. Slow deep breathing is the validated method to …

esophagitis
heartburn
acidity
regurgitation
  • 62 views
  • 09 Aug, 2021
  • 1 location
A Study to Reduce the Reflux After a Sleeve Gastrectomy in Obese Patients

This is a monocentric randomized controlled prospective study. A total of 122 patients will be recruited and randomized 1: 1 in the experimental group - Laparoscopic Sleeve Gastrectomy and Diaphragmatic Pillar Closure - or in the control group - Laparoscopic Sleeve Gastrectomy. At 6 months post surgery a gastroscopy, an …

sleeve gastrectomy
gastroscopy
hiatal hernia
fats
esophageal manometry
  • 17 views
  • 25 Feb, 2021
  • 1 location
Physiology of GERD and Treatment Response

This study is designed to assess the physiologic and behavioral mechanisms associated with enhanced medication effects in adult patients with functional GERD-related symptoms.

heartburn
acidity
  • 92 views
  • 26 Jan, 2021
  • 1 location
Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia

Laryngomalacia (LM) is the most common cause of stridor in infants. Symptoms of gastroesophageal reflux (GER) are often seen in the setting of LM; therefore, acid suppression therapy (AST) has

  • 0 views
  • 27 Jan, 2021
  • 1 location
Gracie Diet for Gastroesophageal Reflux Disease

GERD, is a common and chronic world-wide disease. Cardinal symptoms of this condition are heartburn-regurgitation, and sometimes with extra-intestinal symptoms that can affect patients' quality of life. Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for treatment of acid-related diseases. This class of medications is …

  • 0 views
  • 27 Jan, 2021
  • 1 location
The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

After vonoprazan (20mg/day) or esomeprazole (20mg/day) for 4weeks is prescribed for patients with erosive esophagitis diagnosed by esophagogastroduodenoscopy, the number of patients who will visit our outpatient clinic again due to some reasons without any appointments is compared with vonoprazan group and esomeprazole.

  • 0 views
  • 02 Feb, 2021
  • 1 location
Laparoscopic Gastric Bypass With the Total Wrapping of the Fundus of Gastric Excluded Part for Treating Obesity and GERD

Background and study aims: Currently, one anastomosis Gastric Bypass/Mini Gastric Bypass (OAGB/MGB) is a common bariatric procedure. Obesity and gastroesophageal reflux disease are steadily increasing world weight and antireflux surgery must be performed simultaneously with bariatric surgery in obese patients. In these cases, most often, hiatus cruroraphy is performed, and …

  • 0 views
  • 26 Apr, 2021
  • 1 location
The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study

Gastroesophageal reflux disease related symptoms are reported by 10-20% of the adult population and of those 50-75% report symptoms during sleep time. The prevalence of nocturnal GERD (nGERD) is estimated to be about 25% in general population. nGERD causes sleep fragmentation, difficulty falling asleep, daytime sleepiness, reduced work productivity and …

  • 0 views
  • 15 May, 2021
  • 1 location
A Study to Compare PK PD and Safety of CKD-382 in Healthy Subjects

To compare pharmacokinetics, pharmacodynamics and safety after single/multiple administration of CKD-382 and D026 in healthy subjects

  • 1 views
  • 29 Jan, 2021
  • 1 location
Thresholds of Straight Leg Raise Maneuver During High-Resolution-Manometry

High resolution manometry (HRM) is a key test in the preoperative assessment of patients with gastro-esophageal reflux disease (GERD) who are potential candidates for antireflux surgery. The

  • 0 views
  • 31 Jul, 2021
  • 1 location