Gastroesophageal Reflux Disease (GERD) Clinical Trials

A listing of Gastroesophageal Reflux Disease (GERD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 84 clinical trials
featured
Persistent Acid Reflux Disease

Acid Reflux, Heartburn and currently taking proton pump inhibitors  

  • 101 views
  • 23 Nov, 2020
  • 1 location
featured
Heartburn Acid Reflux Study

GERD Study Pain and discomfort from acid reflux? If so, consider a GERD research study at Carolina’s GI Research.

discomfort
reflux
  • 300 views
  • 23 Nov, 2020
  • 1 location
featured
A research study for subjects with clinically significant heartburn

This study will assess the efficacy and safety of study drug, vonoprazan (20 mg once daily [QD]) compared to lansoprazole (30 mg QD) in the healing and relief of heartburn in subjects with endoscopically proven Erosive Esophagitis (EE).  

lansoprazole
esophagitis
  • 60 views
  • 23 Nov, 2020
  • 1 location
featured
Heartburn study, for people with non-erosive gastroesophageal reflux disease

A research study to evaluate the efficacy and safety of vonoprazan 10 mg, 20 mg, and 40 mg compared to placebo for relief of episodic heartburn in subjects with symptomatic non-erosive gastroesophageal reflux disease.

  • 0 views
  • 31 Mar, 2021
  • 1 location
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A Phase 2b, Randomized, Doubl-blind, Placebo-controlled, Parallel-group, Dose-ranging-finding Trial of XXXXX Administered Orally for 8 Weeks to Patients with Symptomatic Gastroesophageal Reflux Disease Not Completely Responsive to Proton Pump Inhibitors

A Phase 2b, Randomized, Doubl-blind, Placebo-controlled, Parallel-group, Dose-ranging-finding Trial of XXXXX Administered Orally for 8 Weeks to Patients with Symptomatic Gastroesophageal Reflux Disease Not Completely Responsive to Proton Pump Inhibitors

  • 1233 views
  • 08 Nov, 2020
  • 1 location
Impact of an Endoscopic Treatment of the Line Z on the Gastronomic Recurrence and the Gastro- Esophageal Reflux Disease in the Care of the Adenocarcinoma of Barrett's Oesophagus

Barrett's oesophagus is a transformation of the esophageal mucous membrane there intestinal metaplasia under the effect of gastro- esophageal reflux disease (GERD). This metaplasia can

  • 7 views
  • 15 May, 2021
  • 1 location
A Prospective Randomized Trial Comparing Laparoscopic Nissen Against Anterior Partial Fundoplication in Treating Gastroesophageal Reflux Disease Among Chinese Patients

The aim of this study is to compare the effectiveness of laparoscopic Nissen against anterior partial fundoplication in the control of gastroesophageal reflux disease among Chinese patients Study hypothesis Laparoscopic Nissen is comparable to anterior partial fundoplication in the control of gastroesophageal reflux disease

fundoplication
esomeprazole 40 mg
regurgitation
acidity
heartburn
  • 16 views
  • 07 Nov, 2020
  • 1 location
Tongjiang Series Prescription Combined With PPIs Descending Ladder Withdrawal in Treating Nonerosive Reflux Disease

Nonerosive Reflux Disease (NERD) is a common refractory gastrointestinal disease. Proton Pump Inhibitors (PPIs), the preferred drug, have poor response, single target and poor acid inhibition effect in some patients in clinical application. Long-term use of PPI can lead to many side effects, even dependency. The main Traditional Chinese Medicine …

  • 0 views
  • 24 Jan, 2021
  • 1 location
Hiatal Interrogation in Sleeve Gastrectomy

The subject will undergo standard pre-operative preparation. Subjects will be evaluated for the presence of bothersome GERD symptoms by GERD questionnaires and use of Proton-Pump Inhibitor (PPI) medications. Those eligible will be approached at their preoperative appointment about participation in the study and consent will be reviewed with subject. Signed …

  • 3 views
  • 26 Jan, 2021
  • 1 location
Balloon Dilation Methods for Benign Esophageal Stricture

This is the first head to head, prospective, randomized, double-blind clinical trial comparing two different approaches of balloon dilation (standard versus progressive dilation) for benign esophageal strictures. A retrospective study on patients with benign esophageal strictures that underwent balloon dilation using the proposed technique found considerable symptomatic improvement in dysphagia. …

  • 0 views
  • 03 Feb, 2021
  • 1 location