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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (255) clinical trials

Evaluation of a Serious Game for Patients With Bipolar Disorder Involved in a Psychoeducation Group

Bipolife is a serious game for bipolar patients, developed by Astra Zeneca laboratory in collaboration with a french company named Ubisoft. The aim of this interactive tool is to help patient to have a better understanding of their condition and to identify their daily routine which can impact on it. ...

Phase N/A

Cognitive Behavioural Therapy for Social Phobia in People With Bipolar Disorder

Social phobia is a very prevalent anxiety disorder in people with bipolar disorder and is associated with adverse outcomes. Yet, social phobia is treatable by cognitive behavioural therapy or antidepressant medication. As antidepressants are often contra-indicated in people with bipolar disorder, cognitive behavioural therapy is the likely first choice treatment ...

Phase N/A

Effects of Erythropoietin for Cognitive Side-effects of ECT

The trial will include patients with a diagnosis of major depression (MDD) unipolar disorder (UD) or bipolar disorder (BD) with a current moderate to severe depressive episode symptoms (a score of >17 on the Hamilton Depression Rating Scale 17-items (HRDS-17) scheduled for ECT treatment. Patients will be recruited from Psychiatric ...


Cognitive Behavioral Social Skills Training in Early Onset Psychosis

Early-onset of psychotic disorders (EOP), and especially Schizophrenia, is associated with a worse clinical and psychosocial evolution than in the adult form of the illness. In the case of patients with EOP, international and national clinical guidelines recommend the combination of pharmacological treatment with CBT. However there are not any ...

Phase N/A

Emotions in Schizophrenia and Bipolar Disorders: a Common Vulnerability?

The aim of this proposal is to investigate disturbances of understanding of "emotional language" in schizophrenia and bipolar disorder. By "emotional langague", the investigators mean emotions wich can be drawn from utterances, thanks to affective valence of words or phrases, expression of emotional state or prosody. Schizophrenia and bipolar disorder ...

Phase N/A

Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders

Bipolar disorder is a complex, multifactorial disorder with the intervention of genetic vulnerability factors. To help the identification of these genetic factors and to improve genotype-phenotype correlation, the identification of endophenotype through the exploration of vulnerability characteristics in unaffected first degree relatives have been recommended. For this purpose, the investigator ...

Phase N/A

Simvastatin Addition for Patients With Recent-onset Schizophrenia

Rationale: Different lines of evidence now suggest that low grade inflammation in the central nervous system is involved in the pathogenesis of schizophrenia. These include the altered risk of schizophrenia patients and their relatives for specific auto-immune diseases, clinical similarities between the course of schizophrenia and auto-immune disease and decreased ...


Modified Psychodynamic Psychotherapy for Patients With Schizophrenia

Rationale: Compared to the existing evidence for other psychotherapy methods like cognitive-behavioral psychotherapy or family interventions, the scientific basis of psychodynamic psychotherapy for psychoses is weak with respect to randomized-controlled research. Its encouragement by expert opinion and the broad application of this method stands in sharp contrast to the apparent ...

Phase N/A

Bergen Psychosis Project 2 - The Best Intro Study

In the Bergen Psychosis Project 2 the antipsychotic drugs aripiprazole, amisulpride, and olanzapine will be compared head-to-head in patients with schizophrenia and related psychoses and followed for 12 months. The study is independent of the pharmaceutical industry, and in accordance with a pragmatic design a clinically relevant sample will be ...


Mental Time Travel and Identity in Bipolar Disorder Patients

Study design: case / control study in inclusion prospective, single center. population: A group of 30 patients aged 18 to 60 years and followed in the psychiatry department of adult CHU Reims for bipolar disorder type I (DSM-IV criteria). A group of 30 control subjects with no personal or family ...

Phase N/A