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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (328) clinical trials

Cognitive Behavioral Social Skills Training in Early Onset Psychosis

Early-onset of psychotic disorders (EOP), and especially Schizophrenia, is associated with a worse clinical and psychosocial evolution than in the adult form of the illness. In the case of patients with EOP, international and national clinical guidelines recommend the combination of pharmacological treatment with CBT. However there are not any ...

Phase N/A

The Effects of tDCS on Depressive Symptoms Neurocognitive Function and HRV in Unipolar Depression and Bipolar Depression

Background Transcranial direct current stimulation encompasses the induction of a relatively weak constant current flow through the cerebral cortex via scalp electrodes . Dependent on stimulation polarity, this results in a modulation of cortical excitability and spontaneous neural activity. The technique was established in the 1950s and 1960s primarily in ...

Phase N/A

Occupational Stress and Bipolar Disorder

Socio-demographic, psychiatric and occupational data of 200 bipolar patients will be collected over a period of 6 months.

Phase N/A

Gut Microbiome in AP Naive

The objectives of the study are to examine the gut microbiome composition and diversity in patients with schizophrenia, schizoaffective disorder, or other specified schizophrenia spectrum and other psychotic disorder at 6 weeks and 3 months post antipsychotic initiation. Furthermore, the team aims to investigate causality of antipsychotic (AP)-induced changes in ...

Phase N/A

A Survey on Quetiapine Extended-release Tablets in Patients With Depression in Bipolar Disorder

This is a post-marketing use-result survey study required for products in Japan. The investigator will register the patient who have been taking this product for the first time within 14 days after the start of treatment (inclusive of the start day). For each of the registered patients (including withdrawals and ...

Phase N/A

Brexpiprazole for Bipolar Depression

The investigators will conduct an 8-week, non-randomized, open-label study of brexpiprazole in 20 persons with bipolar I or II disorder, depressed mood state. Primary aim will be to assess if brexpiprazole is associated with a reduction in depressive symptom severity using the Montgomery-Asberg Depression Rating Scale (MADRS). Secondary aims will ...


Testing the Value of Smartphone Assessments of People With Mood Disorders

Progress in psychiatry will require better measurement. Currently, few clinicians use standard rating instruments for either diagnosis or outcomes. As a result, clinicians often fail to detect when a patient is not improving and fail to adjust treatments accordingly. Yet even with the use of standard rating instruments, there are ...

Phase N/A

IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2

Investigators propose a randomised double-blinded placebo-controlled trial to test the hypothesis that immunotherapy is an effective treatment of antibody-associated psychosis, either first episode of psychosis or relapse following previous remission. Immunotherapy for the trial consists of one cycle of intravenous immunoglobulin (IVIG: 2g/kg over days 1-4) followed by two infusions ...


Laughter Yoga Intervention for People With Major Depressive Disorder

72 community dwelling people with co-morbid symptoms of depression, anxiety and stress who are diagnosed and treated for major depressive disorder (MDD) will be recruited into the study from the Community Psychiatric Service (CPS) of Castle Peak Hospital. After baseline measurements, 36 participants will be randomly allocated into the Laughter ...

Phase N/A

A clinical trial sponsored by National Institute of Mental Health (NIMH) for a research study for the treatment of Endogenous depression, Post-Traumatic Stress Disorder, Schizophrenia, Bipolar Disorder, Major depression

Objective: The mission of Human Brain Collection Core (HBCC) is to gain insight into the causes and mechanisms of mental disorders. Study Population: To be able to conduct this research, we obtain brain and other tissues from deceased individuals with and without psychiatric disorders. Study Design: This protocol provides the ...

Phase N/A