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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (357) clinical trials

Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS)

Neurocognitive difficulties are a common problem in the older adult population. Previous research has shown memory complaints are higher in older adults with depression or anxiety versus those without these diagnoses. This suggests that mood symptoms, or a diagnosis of a mood disorder, may represent significant predictors of cognitive impairment. ...

Phase N/A

FCT Study: Reducing the Need for Out-of-Home Placements

The goal of this study is to examine the effectiveness of FCT on a number of youth, family, and cost outcomes, as compared to a Level III out-of-home placement. Children who are appropriate for this service may exhibit the following behaviors: Inability to follow directions and conform to structure of ...

Phase N/A

Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

OBJECTIVE During the perimenopause, the incidence of depression increases 1-5 and predicts increased all-cause and cardiovascular mortality. A role of estradiol withdrawal in the onset of mood disorders in some perimenopausal women has been suggested indirectly by estradiol s antidepressant efficacy and safety in perimenopausal depression. Moreover, observational studies report ...


Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy

Winter seasonal affective disorder (SAD) is a subtype of recurrent depression involving major depressive episodes during the fall and/or winter months that remit each spring. The central public health challenge in the management of SAD is prevention of winter depression recurrences. This application focuses on two SAD treatments that each ...


Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy

Physicians and pharmacists have long been aware of subtle differences between patients in their responses to medications, but until recently did not have the tools to predict a patient's response to a drug before prescribing it. Many commonly prescribed medications are either ineffective or cause significant side effects for some ...

Phase N/A

Peer Social Support During In Vivo Exposure for PTSD

Veterans (participants and peers) with PTSD will be recruited from the Charleston VA Medical Center catchment area. Participants will have been assigned to exposure therapy for PTSD and either started treatment, or dropped out before treatment; peers will have successfully completed exposure therapy for PTSD. Those eligible to participate will ...

Phase N/A

Improving Accessibility and Personalization of CR for Schizophrenia

Cognitive remediation (CR) is an evidence-based practice to treat the pervasive and significant cognitive deficits that contribute to functional decline in schizophrenia. The New York State Office of Mental Health (OMH) has teamed with the Principal Investigator to be the first, and largest state system of care to implement a ...

Phase N/A

Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression

This study aims to investigate the clinical efficacy of continuous theta burst stimulation (cTBS) on the right DLPFC as an add-on treatment in bipolar depression. The study consists of three phases. Phase 1: Bipolar depressed patients will be selected by a certified psychiatrist, who will administer (semi-)structured clinical interviews (M.I.N.I.-Plus ...

Phase N/A

Illness Representations in Patients With Bipolar Disorders

Bipolar disorder is a serious and chronic illness representing a major health problem with high mortality rates (Colom and Lam, 2005). According to the self-regulation model (Leventhal, Nerenz & Steel, 1986), patients had some representations of their illness which are cognitive and emotional. Cognitive representations include the set of beliefs ...

Phase N/A

Technology Enabled Collaborative Care for Youth

The overall objective is to develop scalable interventions to address the physical health needs of patients affected by first episode psychosis (FEP). The objective of this project is to conduct a feasibility study of a high intensity Technology-Enabled Collaborative Care (TECC) model compared to lower intensity self-help modules and email ...

Phase N/A