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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (357) clinical trials

A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia Schizoaffective Disorder or First Episode Psychosis on an Oral Atypical Antipsychotic

The advancements in the treatment of mental health patients with DMS will enable healthcare professionals (HCPs) to assess suboptimal adherence and make more informed treatment decisions. In addition to these improvements, it will also provide a platform for engagement between subjects, HCPs, and caregivers/support persons.


Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy

Physicians and pharmacists have long been aware of subtle differences between patients in their responses to medications, but until recently did not have the tools to predict a patient's response to a drug before prescribing it. Many commonly prescribed medications are either ineffective or cause significant side effects for some ...

Phase N/A

Peer Social Support During In Vivo Exposure for PTSD

Veterans (participants and peers) with PTSD will be recruited from the Charleston VA Medical Center catchment area. Participants will have been assigned to exposure therapy for PTSD and either started treatment, or dropped out before treatment; peers will have successfully completed exposure therapy for PTSD. Those eligible to participate will ...

Phase N/A

Improving Accessibility and Personalization of CR for Schizophrenia

Cognitive remediation (CR) is an evidence-based practice to treat the pervasive and significant cognitive deficits that contribute to functional decline in schizophrenia. The New York State Office of Mental Health (OMH) has teamed with the Principal Investigator to be the first, and largest state system of care to implement a ...

Phase N/A

Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression

This study aims to investigate the clinical efficacy of continuous theta burst stimulation (cTBS) on the right DLPFC as an add-on treatment in bipolar depression. The study consists of three phases. Phase 1: Bipolar depressed patients will be selected by a certified psychiatrist, who will administer (semi-)structured clinical interviews (M.I.N.I.-Plus ...

Phase N/A

Illness Representations in Patients With Bipolar Disorders

Bipolar disorder is a serious and chronic illness representing a major health problem with high mortality rates (Colom and Lam, 2005). According to the self-regulation model (Leventhal, Nerenz & Steel, 1986), patients had some representations of their illness which are cognitive and emotional. Cognitive representations include the set of beliefs ...

Phase N/A

Technology Enabled Collaborative Care for Youth

The overall objective is to develop scalable interventions to address the physical health needs of patients affected by first episode psychosis (FEP). The objective of this project is to conduct a feasibility study of a high intensity Technology-Enabled Collaborative Care (TECC) model compared to lower intensity self-help modules and email ...

Phase N/A

Can Imagination Change Upsetting Memories of Trauma?

Research suggests that imagination is a powerful tool to change images inside our heads (e.g. memories) and make them less upsetting. It is thought that this occurs through changing the meaning attached to the memory (e.g. I am weak), therefore making it less upsetting to remember. Research has also linked ...


A Study of Pregnant and Postpartum Women With and Without Mood Disorders

Postpartum Depression (PPD) is a serious syndrome which resembles a major depressive episode and occurs in 10-20% of all mothers in the year following delivery. In addition, 20 - 30 % of women with Bipolar Disorder will experience postpartum psychosis (mania) and at least 20 % will experience a postpartum ...

Phase N/A

Vortioxetine add-on Treatment Improves the Symptoms in Patients With Bipolar Depression

In this study, the investigators are going to examine the efficacy of vortioxetine augmentation in bipolar disorder patients with depressive symptoms. The study design is a double-blinded 6-week prospective study. It would be useful for clinicians because it will provide new evidence for the effect of vortioxetine in bipolar disorder ...