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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found (320) clinical trials

Bipolar Research And Innovation Network - BRAIN

Norway is both social, genetically and culturally a homogeneous society. The health service is public and has a nearly total responsibility for psychiatric care in given catchment areas. This provides excellent opportunities to describe the frequencies and patterns of the broad spectrum of bipolar illness, including co-morbid substance use disorders, ...

Phase N/A

Seasonal Affective Disorder and Visual Impairment

As a subtype of major depressive disorder, seasonal affective disorder (SAD) or winter depression causes severe reductions in both quality of life and productivity and results in high morbidity and frequent sick leave (1). SAD is a prevalent disorder with rates as high as 3-5% in central European countries and ...

Phase N/A

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

A 12-week, randomized, double-blind, parallel-group, placebo-controlled adaptive, Drop The Loser (DTL) design clinical trial of citicoline and pregnenolone will be conducted in 199 outpatients with bipolar I or II disorder or schizoaffective disorder (bipolar type) and current alcohol use disorder. Potential participants will be identified and an appointment will be ...

Phase

Manualized Group Cognitive-behavioral Therapy for Social Anxiety in First Episode Psychosis

Preamble Social anxiety is highly prevalent in people with schizophrenia and related psychotic disorders, and represents a major obstacle to a positive functional outcome. The investigators have recently developed a psychosocial intervention for social anxiety that is specifically tailored to people with psychosis. An adapted Cognitive-Behavioural Therapy (CBT) intervention for ...

Phase N/A

Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD (SUD+BD) have substantially worse clinical outcomes than those with either BD or SUD alone. Nonetheless, ...

Phase

Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders

Clinical assessment Standard clinical practice at the outpatient clinic of the department of psychiatry, at University of Nebraska Medical Center involves an initial clinical interview by either a child and adolescent psychiatrist faculty member, a child and adolescent psychiatry clinical fellow, or an advanced practice registered nurse. The clinical interview ...

Phase

Mood Patient Powered Research Network (MoodNetwork)

The MoodNetwork, a patient-powered research network (PPRN), is one of 18 PPRNs participating in Patient-Centered Outcomes Research Institute's (PCORI) PCORnet network. Its objective is to improve the nation's capacity to conduct comparative effectiveness research that reflects questions of greatest importance to patients and other stakeholders. A robust data infrastructure will ...

Phase N/A

Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study

The Mood Disorder Cohort Research Consortium (MDCRC) study is designed as a naturalistic observational prospective cohort study for early-onset mood disorders (major depressive disorders, bipolar disorders type 1 and 2) in South Korea. The study subjects consist of two populations: 1) patients with mood disorders under 25 years old and ...

Phase N/A

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

The premise of this proposal is that the clinical efficacy of lithium in bipolar disorder, and its complex effects on multiple brain physiological functions, may be best deciphered using a network properties-metric approach. This approach is critical because it provides insight into the function of brain networks (e.g., resilience to ...

Phase N/A

Connectomics in Psychiatric Classification of Bipolar Disorder and Schizophrenia

This study extends the assessment of brain connectivity and function, being conducted in the Human Connectome Project (HCP), to psychiatrically ill populations. The HCP consortium has made significant improvements in MRI instrumentation, data acquisition, preprocessing, and analysis. These improvements are currently providing publicly available data on the structure, function, and ...

Phase N/A