Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 59 clinical trials
A Study of the Change in Disease State and Safety of Oral Cariprazine Capsules in the Treatment of Depression in Pediatric Participants (10 to 17 Years of Age) With Bipolar I Disorder

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive

depressed mood
depressive episode
mood disorder
  • 0 views
  • 16 Jun, 2021
  • 62 locations
Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Background Electroconvulsive therapy (ECT) is used to treat people with severe depression. During ECT, the brain is given electric pulses that cause a seizure. Although it is effective, it can cause side effects, including memory loss. Researchers want to study a new way to give ECT called iLAST. Objective To …

anesthesia
depressed mood
depression
electroconvulsive therapy
depressive disorder
  • 6 views
  • 17 Jun, 2021
  • 1 location
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

Background Some women who had depression in the perimenopause may have mood symptoms again if they stop estrogen therapy. Estrogen acts in the brain and other tissues by binding to at least three types of estrogen receptors. One of these receptors, estrogen receptor beta may affect anxiety and depression. The …

scid
depressive episode
mood symptoms
progesterone
anxiety
  • 107 views
  • 16 Jun, 2021
  • 1 location
Validation of an Automated Online Language Interpreting Tool - Phase Two.

There is a pressing national need to provide higher-quality, more effectively accessible language interpretation services to improve the health outcomes of Americans who have limited English proficiency (LEP). This project addresses a critical component of this problem: The need to improve access to high quality, mental health services for diverse …

mood disorder
drug abuse
alcohol abuse
anxiety
drugs of abuse
  • 110 views
  • 12 Jun, 2021
  • 1 location
Aromatherapy for Improving Post-Surgical Quality of Life

leading to an increase of up to 50% of postoperative pain and opioid requirement. Therefore, the control of mood disorders prior to surgery may help with the perioperative pain management and

  • 0 views
  • 08 Jun, 2021
  • 1 location
Sleep/Wake Cycle and Depression: An Imaging and Treatment Study

abnormalities in circadian rhythms (biological changes that happen over the course of the day or night) are related to mood disorders. This may explain why people with depression frequently suffer with sleeping

  • 0 views
  • 16 Jun, 2021
  • 1 location
Familial Risk for Bipolar Disorder and Alcohol Sensitivity

typically developing age- and sex-matched controls with no parental history of mood disorders or AUDs (N=25 per group). Then, while wearing Secure Continuous Remote Alcohol Monitoring [SCRAM] sensors

alcohol use disorder
  • 0 views
  • 11 Jun, 2021
  • 1 location
Exploring the Effects of Corticosteroids on the Human Hippocampus

patients with mood disorders, as a large subset of people with major depressive disorder (MDD) show evidence of HPA axis activation, elevated cortisol and, importantly, resistance to the effects of CSs on

depressive symptoms
mood disorder
major depressive disorder
depressed mood
depressive disorder
  • 17 views
  • 17 Jun, 2021
  • 2 locations
A Transdiagnostic Course for Common Mental Health Problems in Primary Care

This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care. This is a prospective single-group study where 68 adults with clinically significant symptoms of depression or general anxiety, and up …

covid-19
depressive symptoms
psychiatric symptoms
anxiety
depressed mood
  • 0 views
  • 16 Jun, 2021
  • 1 location
Antidepressant Effects of TS-161 in Treatment-Resistant Depression

Background Major depressive disorder (MDD) is a common, chronic mental illness. It can take weeks to months for antidepressants to work. Researchers want to test a new drug that might act more rapidly. Objective To see if TS-161 will improve symptoms of depression in people with MDD. Eligibility Adults ages …

depressive symptoms
depressed mood
antidepressants
depressive disorder
  • 0 views
  • 16 Jun, 2021
  • 1 location