Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 916 clinical trials
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A Multicenter, Randomized, Flexible-dose, Double-blind Trial of Brexpiprazole Versus Placebo for the Treatment of Adults With Borderline Personality Disorder

Brexpiprazole is a drug being studied as a possible treatment for borderline personality disorder (BPD).  It was first approved in the United States (10 July 2015) for the treatment of schizophrenia and as an adjunctive therapy (add-on therapy) to antidepressants for the treatment of major depressive disorder. The reason for …

  • 134 views
  • 09 Sep, 2020
  • 1 location
featured
A phase 2/3 Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of PRAX-114 in Participants with Major Depressive Disorder

Praxis Precision Medicines is developing PRAX-114 (the study drug) as a possible new treatment for depression.Depression is a common but serious mood disorder. It

depressed mood
mood disorder
depressive symptoms
  • 0 views
  • 24 May, 2021
  • 1 location
Evaluation of a Cognitive Remediation Program for Mood Disorders

Psychotherapeutic management of cognitive disorders in patients suffering from a mood disorder

  • 0 views
  • 25 Jan, 2021
  • 1 location
Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment

Recurrent fall/winter major depression (known as Seasonal Affective Disorder (SAD)) is a prevalent and disruptive disorder whose pathophysiological basis is unknown, but several

depression
recurrent major depressive episodes
thyroid function tests
depressive symptoms
antidepressants
  • 262 views
  • 07 Nov, 2020
  • 1 location
Myths About Bipolar Affective Disorder: The Role of Structured Group Psychoeducation Therapy

This study will examine: 1) The impact of psycho education group therapy sessions relating to beliefs/myths associated with bipolar affective disorder (BAD) on the emotional wellbeing

remission
psychotherapy
mood disorder
bipolar disorder
  • 34 views
  • 07 Nov, 2020
  • 1 location
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder

  • 6 views
  • 22 Jan, 2021
  • 1 location
Tianeptine for Treatment Resistant Depression

The study will be conducted in parallel at two sites: the Clinic for Aging, Anxiety and Mood Disorders (CAAM) at Columbia University/New York State Psychiatric Institute (CU/NYSPI) and the Mood

bupropion
snri
antidepressants
depressive disorder
mirtazapine
  • 0 views
  • 26 Jan, 2021
Repetitive Transcranial Magnetic Stimulation for Adolescent Depression: Efficacy Predictive Biomarkers and Mechanisms

This study will be an open-label 6-week (30 session) trial of active repetitive transcranial magnetic stimulation (rTMS) using a fixed frequency (10 Hz) but varying stimulation intensities using a 3+3 study design for safety and tolerability amongst adolescents. This means that we will only enroll 3 participants at a time …

transcranial magnetic stimulation
depressive disorder
  • 113 views
  • 25 Jan, 2021
  • 1 location
Reward Circuit Modulation Via fMRI-informed-EEG-based Musical Neurofeedback

The goal of this study is to test whether voluntary up-regulation of mesolimbic reward system activation is possible, and to examine the neurobehavioral effects of specific neuromodulation of this circuit on reward processing. This goal will be achieved by testing the effects of a novel non-invasive experimental framework for neuromodulation …

  • 0 views
  • 15 May, 2021
  • 1 location
Adapting a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

All patients with serious mental illness are abstinent while in the hospital for a psychiatric admission yet almost all return to smoking after discharge. The investigators propose to adapt a digital intervention both to the needs of SMI smokers and to being introduced in the inpatient psychiatric setting through a …

  • 0 views
  • 10 May, 2021
  • 1 location