Peripheral Arterial Disease (PAD) Clinical Trials

A listing of Peripheral Arterial Disease (PAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 164 clinical trials
A Study Evaluating the Endovascular Treatment of Subjects With Stenotic or Restenotic Lesions of the Common Femoral Artery With the Supera Vascular Mimetic Implant Compared to Surgical Common Femoral Artery Endarterectomy

The SUPERSURG RCT trial investigates the efficacy and safety of the endovascular treatment of stenosis or restenosis in the common femoral artery (CFA) of patients presenting with Rutherford classification 2,3 or 4 with a Supera Vascular Mimetic Implant of Abbott, compared to classic surgical common femoral artery endarterectomy. The Supera …

  • 18 Sep, 2021
  • 10 locations
Arterial Dissections After Angioplasty by Long vs Short Time of Balloon Inflation: the Randomized Controlled Trial.

Background. Arterial dissections represent the typical complication of the percutaneous transluminal angioplasty for femoropopliteal disease and have negative impact upon the outcomes of the treatment. Objective. The study is aimed to test the hypothesis that a prolonged (6 minutes) time of inflation of angioplasty balloon would reduce the rate of …

vascular surgical procedures
balloon angioplasty
  • 24 Jan, 2021
  • 1 location
Exercise and Weight Loss in PAD (Action3)

This study is designed to examine the added benefits of weight loss to an exercise program in older obese Veterans with peripheral arterial disease. The investigators want to determine if weight loss in addition to exercise will 1) improve walking ability to a greater extent than exercise alone and 2) …

intermittent claudication
vascular disease
  • 26 Apr, 2022
  • 1 location
Moderate Intensity Functional Training as Adjuvant Treatment in Patients With Peripheral Arterial Disease

peripheral arterial disease (PAD). However, the transfer of the current resistance exercise modes proposed to other activities of daily living (ADLs) is questionable. Moderate intensity functional training

  • 26 Nov, 2021
  • 1 location
Exercise Therapy for PAD Using Mobile Health

Peripheral artery disease (PAD) is a highly prevalent condition affecting up to 10% of Veterans that leads to loss of walking ability and increased risk of amputation. Veterans have limited

  • 15 Dec, 2021
  • 1 location
The Effects of Claudication Severity on Functional Outcomes

Peripheral artery disease (PAD) affects over 236 million people globally. A classic symptom of PAD is intermittent claudication (IC) which is associated with reductions in physical function. The

  • 13 Aug, 2021
  • 1 location
Efficacy of Subintimal vs Intraluminal Approach for Atherosclerotic Chronic Occlusive Femoropopliteal Arterial Disease

There are two ways of approaching atherosclerotic chronic occlusive femoro-popliteal arterial lesion with guide wire. One is the intraluminal approach of passing guide wire through the atheroma, the other is the subintimal approach of passing wire through the subintima of the vessel. Either of these two interventional technique can be …

atherosclerotic lesion
intravascular ultrasound
critical limb ischemia
  • 25 Jan, 2021
  • 3 locations
Treatment of No-option CLI by G-CSF-mobilized PB-MNC

This study will investigate the efficacy of G-CSF mobilized mononuclear cell injection of patients with PAD who presented with no-option CLI. Forty no-option CLI patients who presented with rest pain, non-healing ischemic ulcer or gangrene will be randomized into 2 groups. The control group will be treated by medication and …

granulocyte colony stimulating factor
rest pain
ischemic ulcer
  • 14 Feb, 2022
  • 1 location
High Intensity Interval Training In pATiEnts With Intermittent Claudication (INITIATE)

This INITIATE study evaluates the use of high-intensity interval training as a treatment modality for patients with intermittent claudication - an ambulatory leg pain caused by narrowed arteries that supply the lower limbs. It is an observational cohort study considering HIIT as a treatment for intermittent claudication, consisting of two …

leg pain
intermittent claudication
  • 14 Feb, 2022
  • 1 location
Prospective Case-control Study in Patients With PAA

The overall objective is to highlight different aspects of care in patients with PAA before and after treatment, and identifying factors that influence the outcome of PAA patients.

intermittent claudication
  • 20 Feb, 2022
  • 2 locations