Peripheral Arterial Disease (PAD) Clinical Trials

A listing of Peripheral Arterial Disease (PAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 153 clinical trials
Hypoxic Exercise in Lower Extremity Artery Disease

The aim of this randomized controlled trial is to: Phase I: To explore, in a first pilot phase, the adequate combination of hypoxia severity and exercise intensity in patients with symptomatic lower extremity artery disease (LEAD). Acute walking performances and physiological responses (vascular and muscular) to a normobaric hypoxic exercise …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Carnosine for Peripheral Vascular Disease

The investigators hypothesise that a home-based standardised exercise intervention with 2g of carnosine daily for 6 months will improve walking endurance in 104 patients with PVD aged 40-80 years compared to placebo and exercise through stabilisation of HIF1- in the ischaemic leg. Aims Aim 1: Determine whether in patients with …

  • 4 views
  • 27 Jan, 2021
  • 1 location
A Study Evaluating the Endovascular Treatment of Subjects With Stenotic or Restenotic Lesions of the Common Femoral Artery With the Supera Vascular Mimetic Implant Compared to Surgical Common Femoral Artery Endarterectomy

The SUPERSURG RCT trial investigates the efficacy and safety of the endovascular treatment of stenosis or restenosis in the common femoral artery (CFA) of patients presenting with Rutherford classification 2,3 or 4 with a Supera Vascular Mimetic Implant of Abbott, compared to classic surgical common femoral artery endarterectomy. The Supera …

stenosis
revascularisation
stenotic
  • 0 views
  • 18 Sep, 2021
  • 10 locations
A Prospective, Multicenter Atherectomy Study Showing Luminal Gain in Subjects With Peripheral Vascular Blockages

To evaluate the safety and effectiveness of the DABRA Laser System in the atherectomy of peripheral vascular stenoses.

stenosis
stenotic
luminal
angiography
atherectomy
  • 3 views
  • 06 Jun, 2022
  • 5 locations
Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients

Title: Impacts of mitochondrial-targeted antioxidant on leg blood flow and skeletal muscle mitochondrial function in peripheral artery disease patients. Peripheral artery disease (PAD) is

diabetes
cardiovascular disease
treadmill test
arteriopathy
intermittent claudication
  • 5 views
  • 01 Jul, 2022
  • 1 location
Remote Monitoring of Home Exercise in Peripheral Arterial Disease (ROMEPAD)

Many patients with blockages in the arteries in their legs (peripheral arterial disease, "PAD") suffer from pain in their legs when walking. Exercise therapy is known to decrease pain levels as

  • 0 views
  • 25 Mar, 2022
Vascular Effects Through Sirolimus vs. Paclitaxel DCB Implantation

Endovascular treatment of symptomatic atherosclerotic peripheral artery disease (PAD) is recommended as the primary revascularization strategy. Percutaneous transluminal angioplasty (PTA) of the

  • 0 views
  • 24 Jul, 2022
STEPUP Clinical Trial

This study will test whether, among patients undergoing surgery for peripheral artery disease (PAD), the addition of an online multimedia patient education video to the current education regimen

  • 0 views
  • 22 Jul, 2022
  • 1 location
Treatment of No-option CLI by G-CSF-mobilized PB-MNC

This study will investigate the efficacy of G-CSF mobilized mononuclear cell injection of patients with PAD who presented with no-option CLI. Forty no-option CLI patients who presented with rest pain, non-healing ischemic ulcer or gangrene will be randomized into 2 groups. The control group will be treated by medication and …

granulocyte colony stimulating factor
rest pain
ischemic ulcer
gangrene
  • 3 views
  • 14 Feb, 2022
  • 1 location
High Intensity Interval Training In pATiEnts With Intermittent Claudication (INITIATE)

This INITIATE study evaluates the use of high-intensity interval training as a treatment modality for patients with intermittent claudication - an ambulatory leg pain caused by narrowed arteries that supply the lower limbs. It is an observational cohort study considering HIIT as a treatment for intermittent claudication, consisting of two …

leg pain
intermittent claudication
  • 53 views
  • 14 Feb, 2022
  • 1 location