Peripheral Arterial Disease (PAD) Clinical Trials

A listing of Peripheral Arterial Disease (PAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 153 clinical trials
A Study on the Phenomenon of Remote Ischaemic Preconditioning in Patients With Peripheral Artery Disease

This study aims to evaluate whether remote ischemic preconditioning (RIPC) daily for 28 days reduces the symptoms of intermittent claudication in patients with peripheral artery disease (PAD

  • 08 Jun, 2022
  • 1 location
Smartstep Smartphone PAD (SMARTSTEP)

The study aim is to evaluate the effectiveness of a coached, smartphone-enabled exercise program versus physician directed exercise therapy (usual care).

intermittent claudication
exercise therapy
  • 05 Mar, 2022
  • 1 location
Treatment of Intermittent Claudication by G-CSF-mobilized PB-MNC

This study will investigate the efficacy of G-CSF mobilized mononuclear cell injection of patients with PAD who presented with intermittent claudication. Forty PAD patients who presented with intermittent claudication will be randomized into 2 groups. The control group will be treated by medication and walking exercise 3 times/ week. The …

arterial occlusive disease
intermittent claudication
  • 14 Feb, 2022
  • 1 location
The Impact of Branched-Chain Amino Acid Metabolism on Limb Dysfunction in PAD

Test the theory that abnormalities in the large blood vessels that deliver blood to your leg and the very small blood vessels in your leg's muscles (invisible to the eye) work together to worsen your leg function and walking.

Accepts healthy volunteers
  • 04 Mar, 2022
  • 1 location
A Superiority Trial of the SUPERA Peripheral Stent System in Patients With Femoro-popliteal Artery Disease

The purpose of this study (superiority trial) is to compare the Supera Peripheral Stent System with a standard nitinol self-expanding stent for treatment of femoro-popliteal arterial occlusive disease. Hypothesis The Supera stent is superior to a standard nitinol self-expanding stent, for treatment of femoro-popliteal artery disease in terms of (1) …

arterial occlusive disease
transluminal angioplasty
  • 11 Feb, 2022
  • 1 location
Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization (TAP-DANCE)

This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). …

limb ischemia
intermittent claudication
endovascular procedure
  • 26 Feb, 2022
  • 8 locations
Intermittent Pneumatic Compression to Improve Revascularization Outcome

The purpose of this study is to investigate whether daily treatment with intermittent pneumatic leg compressions (IPC) following a nonsurgical vascular procedure improves circulation and enhances walking distance.

endovascular revascularization
computed tomography angiography
obstructive disease
  • 01 Mar, 2022
  • 1 location
Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease

The prevalence of peripheral arterial disease is 12.2% in France. Intermittent claudication is the most common symtom of this disease. During physical exercise, such as walking, blood oxygen (O2) requirements increase. The development of atherosclerosis in the lower limbs, causes narrowing of the arteries and limits the increase in blood …

  • 24 Mar, 2021
  • 1 location
MyPADMGT Support of Out-Patients With Peripheral Arterial Disease

The investigators have developed an online program to help people with peripheral arterial disease (PAD) in their extremities to better self-manage their condition. Some earlier testing has been

  • 21 Mar, 2021
  • 1 location
A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

Randomized multicenter clinical trial consisting of two arms; one arm treated with PTA plus the MicroStent® System and one arm treated with PTA alone. Purpose to evaluate the safety and effectiveness of using the MicroStent® Peripheral Vascular Stent System, hereafter referred to as the MicroStent® System, for the treatment of …

vascular disease
limb ischemia
critical limb ischaemia
  • 21 Apr, 2022
  • 14 locations