Peripheral Arterial Disease (PAD) Clinical Trials

A listing of Peripheral Arterial Disease (PAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 174 clinical trials
Genotype-guided Strategy for Antithrombotic Treatment in Peripheral Arterial Disease.

Rationale: Peripheral arterial disease (PAD) is a common presentation of atherosclerosis. For the prevention of adverse events related to arterial thrombosis in PAD patients, clopidogrel is

gangrene
intermittent claudication
atherosclerosis
clopidogrel
  • 0 views
  • 08 Jul, 2021
  • 11 locations
Randomized Preventive Vascular Screening Trial of 65-74 Year Old Men in the Central Region of Denmark

Well-documented health benefits may be achieved through prophylactic screening for cardiovascular disease. The advantages are fewer premature deaths and a reduction in the number of hospital admissions and amputations. Furthermore, hospitals will benefit from the derived reduction in the pressure on surgery and intensive care capacities at vascular surgery departments. …

aortic aneurysm
vascular disease
arteriopathy
vascular surgery procedure
atherosclerosis
  • 34 views
  • 23 Jan, 2022
  • 1 location
The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM

This trial is a pivotal, placebo-controlled, double-blind, parallel-group, adaptive trial conducted in subjects with DM and CLI Rutherford Category 5. Minimisation will be used to assign eligible subjects in a 2:1 ratio to receive a single intra-arterial administration of REX-001 or matching placebo into the index limb.

hemoglobin a1c
glycosylated hemoglobin
revascularisation
ischemic ulcer
estrogen
  • 36 views
  • 12 May, 2021
  • 35 locations
Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease

The TRACK trial is an investigator-initiated, multicentre, prospective, randomised, double-blind, placebo-controlled trial. TRACK is a global trial and will be conducted in renal units that provide comprehensive CKD care. Approximately 2000 participants will be recruited. The TRACK trial will assess a strategy of administering low dose rivaroxaban to reduce the …

dialysis
  • 2 views
  • 22 Dec, 2021
  • 34 locations
HELicobacter Pylori Screening to Prevent Gastrointestinal Bleeding in MI Patients

Background: Potent antithrombotic therapy has improved prognosis for patients with acute myocardial infarction (MI) significantly, however, at a price of increased bleeding risk. Helicobacter pylori (H. pylori) infection commonly causes upper gastrointestinal bleeding (UGIB). If systematic screening for H. pylori and subsequent eradication therapy significantly reduces the risk of UGIB …

heart failure
stroke
infarct
fasting
myocardial infarction
  • 0 views
  • 01 Dec, 2021
  • 35 locations
Transfusion Trigger After Operations in High Cardiac Risk Patients

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

percutaneous coronary intervention
exercise stress test
ischemia
cancer
stroke
  • 12 views
  • 16 May, 2021
  • 16 locations
Danish Cardiovascular Screening Trial II

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.

cardiovascular disease
  • 7 views
  • 22 Jan, 2021
  • 4 locations
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).

antioxidant
vitamin e
  • 0 views
  • 02 Sep, 2021
  • 1 location
Peripheral Artery Disease (PAD) : Its Effects on Bone

Prevalence of PAD and osteoporosis (OP) both get higher with age. Clinical and epidemiologic evidence have showed an increased cardiovascular risk in OP and bone loss and fragility fractures in patient with cardiovascular disease. This study will examine the relationship between vascular disease in legs and sBMD and vBMD at …

  • 0 views
  • 12 Sep, 2021
  • 1 location
Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

The PROVE Trial is a randomized clinical trial that will determine whether a weight loss intervention combined with walking exercise achieves greater improvement or less decline in six-minute walk distance at 12 month follow-up than walking exercise alone in people with PAD and BMI>28 kg/m2. The intervention uses a Group …

arteriopathy
peripheral arterial diseases
  • 20 views
  • 16 May, 2021
  • 1 location