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Peripheral Arterial Disease (PAD) Clinical Trials

A listing of Peripheral Arterial Disease (PAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (169) clinical trials

If you are 50 years of age or older and suffer from pain in your lower legs, you may be eligible to participate in a clinical research study. This study will evaluate the safety and effectiveness of an investigational medication in reducing heart disease in individuals diagnosed with PAD. There ...

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Endeavor Clinical Trials is conducting a research study evaluating the safety and efficacy of an intramuscular injection in people with Peripheral Artery Disease & Diabetic Foot Ulcers

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The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death in patients with coronary or peripheral artery disease.

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A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Lutonix 035 Drug Coated Balloon Catheter in Arteries of the Superficial Femoral Artery (SFA) and Popliteal Artery (PA) (SAFE_DCB U.S. Registry) Purpose: The purpose of this patient registry is to assess the clinical use of the Lutonix® ...

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The purpose of this research study is to apply investigational MRI techniques to check blood flow and oxygen in the lower legs and feet of people with and without diabetes or peripheral vascular disease and with and without a foot wound. There are 3 to 4 visits that last 1 to ...

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Elutax-SV Drug-eluting Balloons for Below-the-knee Treatment

The management of critical limb ischemia due to below-the-knee disease remains challenging due to the frequent patient comorbidities, diffuse vascular involvement, limb preservation, and high rates of restenosis and disease progression. This study will record the use of ELUTAX SV-DEB under real life conditions in a representative sample.The investigators will ...

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SDF1 Plasmid Treatment for Patients With Peripheral Artery Disease

To investigate the efficacy of the administration of JVS-100 delivered via direct intramuscular injections on a 3 month and 6 month composite endpoint of wound progression, healing and limb loss in patients with severe peripheral arterial disease with non-healing chronic wounds who undergo an open bypass grafting or endovascular procedure ...


Orbital Vessel PreparaTIon to MaximIZe Dcb Efficacy in Calcified Below the Knee (BTK) Lesions - A Pilot Study

The purpose of this study is to prospectively evaluate acute and long term clinical results of orbital atherectomy (OA) with adjunctive drug coated balloon (DCB) angioplasty versus DCB angioplasty alone for treatment of Peripheral Artery Disease (PAD) in below the knee (BTK) lesions.

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Safety and Feasibility of SurModics SurVeil (TM) Drug Coated Balloon

PREVEIL will enroll patients presenting with angiographic evidence of significant stenosis in the femoral or popliteal arteries. All enrolled subjects will be treated with the SurVeil DCB.

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An Evaluation of a Clinical Algorithm With Turbo-Power Following Treatment of Specific Morphologies

Purpose: To evaluate vessel lumen quality (gain) and patient outcomes based on treatment with a predetermined laser treatment protocol in patients presenting with varying lesion types or morphologies: homogenous (plaques with a uniform texture-smooth and regular), heterogeneous (plaques with non-uniform texture-smooth and irregular surface), calcific (consisting of calcium) and restenotic ...

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