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Atopic Dermatitis Clinical Trials

A listing of Atopic Dermatitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (73) clinical trials

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIES; Job's syndrome) is caused by STAT3 mutations, and is a multisystem disorder with skeletal, vascular, and connective tissue manifestations. Understanding how STAT3 mutations cause these diverse clinical ...

Phase N/A

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Objectives To define the cellular and molecular biomarkers of atopic dermatitis in skin biopsies and blood samples from a pre-adolescent pediatric population and correlate it with disease severity. To measure the skin barrier in atopic dermatitis. To determine quality of life in atopic dermatitis through various questionnaires.

Phase N/A

Cesarean Section Study

Effect, tolerance and safety of a supplementation with a probiotic on the risk of gastrointestinal infections, on growth, and on gut microbiota in healthy newborn term infants born by Cesarean section. Exploratory comparison between a probiotic vs. placebo in the formula-fed and in the breastfed feeding groups.

Phase N/A

Detection and Characterization of Infections and Infection Susceptibility

This screening study is designed to evaluate patients with suspected or identified recurrent or unusual infections and their family members for clinical and in vitro correlates of exposure and susceptibility. It will allow for up to 2 visits to obtain blood, urine, saliva, stool, skin biopsy, or wound drainage from ...

Phase N/A

Collection of Lung Fluid and Tissue Samples for Research

This research protocol involves one or more of the following procedures in healthy volunteers and patients with known or suspected predisposition to respiratory infection who are enrolled in National Institutes of Health (NIH) protocols: 1) Adults only: bronchoscopy with sampling of bronchoalveolar lavage fluid and epithelial cells in healthy adult ...

Phase N/A

Potential Research Study Participant Registry

Methods Subjects will self identify themselves via the UCDMC Dermatology website to complete a survey regarding their interest in learning about future dermatology clinical research projects. Subjects provide contact information and check of a list of potential topics of interest. Procedures Potential participants will find a link on the UCDMC ...

Phase N/A

Role of Tyrosine Kinase Lyn and Cleaved Form by Caspases in Psoriasis

Psoriasis is a chronic autoimmune disorder of the skin. In this disease, the inflammatory caspases, cysteine proteases involved in the processing of many proteins, are activated. Transgenic mice expressing the cleaved form of caspases by Lyn, a tyrosine kinase Src family, develop an inflammatory syndrome with the characteristics of human ...

Phase N/A

Systemic Therapies for Pediatric Atopic Dermatitis

Severe and/or refractory cases of atopic dermatitis (AD) can require systemic immunosuppressive therapy for disease control, yet there are few studies regarding the appropriate use of these drugs for pediatric AD and even less data comparing them. The current observational study will observe the effect of these therapies on children ...

Phase N/A

Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Atopic Dermatitis

Up to 40 healthy and 40 atopic dermatitis subjects meeting the inclusion criteria will be enrolled. Medical records will be reviewed pertaining to the subject's diagnosis of atopic dermatitis and specific therapeutic interventions. For atopic dermatitis subjects, AD severity will be assessed using Eczema Area and Severity Index (EASI). Study ...

Phase N/A

Haut-Tief Patient Education on Psoriasis and Eczema

The educational program consists of 2-hours of educational (dermatology, specialized nurse, psychologist) and stress-reduction sessions (yoga, meditation, physiotherapy) twice a week during 9 weeks. A multidisciplinary team of trainers is involved. Primary endpoint is the general and skin dependent quality of life measured by questionnaires. HRQoL (Health-Related Quality of Life) ...

Phase N/A