Gastroenteritis Clinical Trials

A listing of Gastroenteritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 551 clinical trials
Efficacy Safety and Immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in Neonates

This phase III trial aims to assess the efficacy, safety and immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in neonates, lot-to-lot consistency, and antigen interference with co-administered EPI vaccines

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Clinical Trial of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

The purpose of the research is to evaluate the safety and tolerability of the tetravalent recombinant Norovirus vaccine at different doses, to initially explore the immunogenicity of the vaccine, and to determine the appropriate dose of the product for later clinical trials.This trial adopts the seamless design of phase I/IIa, …

  • 0 views
  • 25 Jan, 2021
  • 1 location
A Trial to Assess the Safety Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India

will receive both TV P2-VP8 IM as well as oral placebo vaccine, and infants allocated to receive Rotarix will receive both Rotarix PO and placebo IM. Active surveillance for episodes of gastroenteritis

  • 0 views
  • 15 Apr, 2021
  • 1 location
Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia

gastroenteritis. Additionally, previous studies show mucosal eosinophilia is highly correlated with functional dyspepsia. Our usual current treatment pathway for functional dyspepsia in association with duodenal

endoscopy
abdominal pain
mast cells
budesonide
mast cell stabilizers
  • 14 views
  • 25 Jan, 2021
  • 1 location
Cross-reactive Immunity Elicited by Oral and Parenteral Typhoid Vaccines

In a recent controlled study, the investigators explored cross-reactive immune responses against different Salmonella spp. in healthy volunteers immunized with either the oral (Vivotif ) or parenteral (Typherix) typhoid vaccines (ISRCTN68125331). In the present study immune responses will be studied in a group receiving both of these vaccines and in …

  • 7 views
  • 08 Nov, 2020
  • 2 locations
Improvements Through the Use of a Rapid Multiplex PCR Enteric Pathogen Detection Kit in Children With Hematochezia

Children presenting for emergency department (ED) care with bloody diarrhea (i.e. hematochezia) represent a diagnostic challenge. Infectious enteric pathogens - Salmonella, Shigella and Shiga toxin-producing Escherichia coli (STEC) - are at the top of the differential diagnosis list. STEC is of greatest concern because ~15% of infected children develop the …

  • 4 views
  • 26 Jan, 2021
  • 1 location
Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis

A phase III, double-blind, parallel-design, randomized, placebo controlled trial to compare multi-dose oral Ondansetron with placebo as treatment for vomiting secondary to acute gastroenteritis

gastroenteritis
acute gastroenteritis
vomiting
ondansetron oral
ondansetron
  • 14 views
  • 26 Jan, 2021
  • 6 locations
Clinical Trial to Evaluate the Recombinant Norovirus Bivalent (GI. 1 / GII. 4) Vaccine (Hansenula Polymorpha)

Phase II clinical study will explore dose and safety, immunogenicity in 4 age groups, including 18-59 years old group, 6-17 years old group, 3-5 years old group, 6-35 months old group, with a total of 1716 subjects.

  • 0 views
  • 12 Jul, 2021
  • 1 location
Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

Rationale and Aim: The standard treatment for acute appendicitis in children is appendectomy. An increasing body of evidence from the adult literature suggests that acute appendicitis may be treated effectively with antibiotics alone, avoiding the need for surgery. The aim of this study is to investigate the effectiveness of non-operative …

appendectomy
antibiotics
anesthesia
ruptured appendicitis
antibiotic therapy
  • 57 views
  • 29 Jan, 2021
  • 1 location
Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy

This study evaluates the effects of preoperative delay and antibiotics on perforation rate of appendix while waiting surgery for acute appendicitis. Patients with diagnosed acute appendicitis are randomized into two urgency groups: surgery within 8 hours or surgery within 24 hours. In addition, patients are randomized to either receive antibiotics …

MRI
appendectomy
metronidazole
antibiotics
antibiotic therapy
  • 0 views
  • 25 Jan, 2021
  • 2 locations